Chia Ling Lee

US Patent:

20130280204, Oct 24, 2013

Filed:

Mar 15, 2013

Appl. No.:

13/839787

Inventors:

Massachusetts Institute of Technology - , US
Chia Min Lee - Cambridge MA, US
Alexander M. Klibanov - Boston MA, US
Jianzhu Chen - Lexington MA, US

International Classification:

A61K 47/48

US Classification:

424 7817, 525436

Abstract:

Antiviral compositions containing one or more antiviral agents coupled to a polymer and methods of making and using the compositions, are described herein. The one or more antiviral agents are covalently coupled to the polymer, and thereby prevent or decrease development of drug resistance. In some embodiments, the polymer is a biodegradable polymer. In particular embodiments, the polymer is a water-soluble, biodegradable polymer, which has an overall neutral charge (e.g., no charged groups or overall neutral charge). In a more particular embodiment, the neutral polymer is polyglutamine or a polymer having properties similar to polyglutamine, polyaspartate, and other homopolypeptides that can be modified to have no charge or no net charge. The compositions described herein are effective at treating a variety of viral infections, such as influenza, respiratory syncythial virus, rhinovirus, human metaneumovirus, and other respiratory diseases, while inhibiting or preventing the development of resistance.

US Patent:

20210312783, Oct 7, 2021

Filed:

Apr 1, 2020

Appl. No.:

16/837781

Inventors:

- Chicago IL, US
YANYAN HU - Medford MA, US
QIFAN LIANG - Quincy MA, US
KANGYAN LIU - Revere MA, US
YIN WANG - Woburn MA, US
WEIJUAN WU - Winchester MA, US
CHIA YING LEE - Medford MA, US

International Classification:

G08B 21/18
G06Q 50/26
G06N 20/00
G06N 5/04

Abstract:

Methods for detecting anomalies in a geographic area include receiving, from an electronic computing device, expected relationship data indicating expected relationships between a plurality of entities within the geographic area; detecting the plurality of entities within the geographic area; generating observed relationship data indicating observed relationships between the plurality of entities; identifying the expected relationships between the plurality of entities based on the expected relationship data; determining that a given observed relationship between two entities of the plurality of entities is likely to represent an anomaly based on the expected relationship data; and providing an electronic notification to a safety officer, the electronic notification indicating that the given observed relationship is likely to represent the anomaly.

US Patent:

20200097769, Mar 26, 2020

Filed:

Sep 18, 2019

Appl. No.:

16/575297

Inventors:

- Vancouver, CA
Yin Wang - Malden MA, US
Xiao Xiao - Reading MA, US
Hao Zhang - Winchester MA, US
Chia Ying Lee - Medford MA, US

Assignee:

Avigilon Corporation - Vancouver

International Classification:

G06K 9/62
G06K 9/20
G06K 9/00

Abstract:

Methods, systems, and techniques for object detection and tracking are provided. A system may include a module configured to generate a plurality of region proposals, each region proposal comprising a part of a video frame, a CNN pre-trained for object detection, the plurality of region proposals being input to the CNN; a tracker for tracking one or more targets based on outputs from the CNN across the series of video frames and generating tracking information on the one or more targets; and a module further configured to refine the plurality of region proposals to be input to the CNN, based on the tracking information.