Chris David Fletcher

US Patent:

7422693, Sep 9, 2008

Filed:

Jul 1, 2004

Appl. No.:

10/884877

Inventors:

Lee F. Carter - Lakewood CO, US
Jeremy P. Kolenbrander - Brighton CO, US
James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeffrey A. Steward - Lakewood CO, US
Chris Fletcher - Superior CO, US

Assignee:

Caridianbct, Inc. - Lakewood CO

International Classification:

B04B 9/10

US Classification:

210745, 210 94, 2105121, 210787, 250573, 250574, 494 1, 494 7, 494 10, 494 37

Abstract:

The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods, devices and device components for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. In embodiment, two-dimensional distributions of transmitted light intensities, scattered light intensities or both measured by the methods of the present invention comprise images of a separation chamber or component thereof, such as an optical cell of a separation chamber. In another aspect, the present invention relates to multifunctional monitoring and control systems for blood processing, particularly blood processing via density centrifugation. Feedback control systems are provided wherein two-dimensional distributions of transmitted light intensities, scattered light intensities or both are measured, processed in real time and are used as the basis of output signals for controlling blood processing.

US Patent:

7605388, Oct 20, 2009

Filed:

Jul 7, 2008

Appl. No.:

12/168192

Inventors:

Lee F. Carter - Lakewood CO, US
Jeremy P. Kolenbrander - Brighton CO, US
James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeffrey A. Steward - Lakewood CO, US
Chris Fletcher - Superior CO, US

Assignee:

CaridianBCT, Inc. - Lakewood CO

International Classification:

G01N 15/06
G01N 21/49
G01N 21/85

US Classification:

250573, 2502222, 356 39, 73 6148

Abstract:

The invention relates to an optical cell for a separation chamber of a density centrifuge blood processing system for separating fluid components comprising an extraction chamber having a first external optical surface for transmitting at least a portion of an incident optical beam; and an extraction port having an axial bore for passing fluid components and a first external optical surface for transmitting at least a portion of the incident optical beam; wherein said first external optical surface of said extraction chamber and said first external optical surface of said extraction port are both positioned within the depth of field of a light collection element.

US Patent:

7906771, Mar 15, 2011

Filed:

Sep 17, 2009

Appl. No.:

12/561419

Inventors:

Lee F. Carter - Lakewood CO, US
Jeremy P. Kolenbrander - Brighton CO, US
James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeffrey A. Steward - Lakewood CO, US
Chris Fletcher - Superior CO, US

Assignee:

CaridianBCT, Inc. - Lakewood CO

International Classification:

B04B 13/00

US Classification:

250573, 494 1, 210745

Abstract:

The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components. In one aspect, the invention relates to optical methods for measuring two-dimensional distributions of transmitted light intensities, scattered light intensities or both from a separation chamber of a density centrifuge. The method may include performing first and second measurements of an operating condition; analyzing the first and second measurements using a predictive data analysis algorithm; comparing the predicted operating condition to a desired operating condition; and adjusting at least one setting.

US Patent:

7943916, May 17, 2011

Filed:

Sep 17, 2009

Appl. No.:

12/561479

Inventors:

Lee F. Carter - Lakewood CO, US
Jeremy P. Kolenbrander - Brighton CO, US
James R. Ladtkow - Broomfield CO, US
Joseph A. Scibona - Littleton CO, US
Jeffrey A. Steward - Lakewood CO, US
Chris Fletcher - Superior CO, US

Assignee:

CaridianBCT, Inc. - Lakewood CO

International Classification:

B01D 37/04

US Classification:

250573, 2502222, 356 39, 73 48

Abstract:

The invention relates generally to methods of monitoring and controlling the processing of blood and blood samples, particularly the separation of blood and blood samples into its components with a two-dimensional optical measurement and control device. The method may comprise the steps of providing a blood processing system comprising a density centrifuge blood processing system and an elutriation blood processing system; filling the elutriation blood processing system with a desired component; measuring a cellular flux of cells entering the elutriation blood processing system with a two-dimensional optical control system; and flushing the elutriation blood processing system.