Christopher B Clark

US Patent:

20130262357, Oct 3, 2013

Filed:

Sep 13, 2012

Appl. No.:

13/613980

Inventors:

Rubendran Amarasingham - Dallas TX, US
Timothy S. Swanson - Grapevine TX, US
Christopher A. Clark - Dallas TX, US
Yu Qian - Irving TX, US
Sambamurthy Nalla - Flower Mound TX, US
George R. Oliver - Southlake TX, US
Kimberly P. Gerra - Keller TX, US
Ying Ma - Southlake TX, US

International Classification:

G06F 19/00

US Classification:

706 21

Abstract:

A clinical predictive and monitoring system comprising a data store operable to receive and store data associated with a plurality of patients selected from medical and health data; and a number of social, behavioral, lifestyle, and economic data; at least one predictive model to identify at least one high-risk patient associated with at least one medical condition; a risk logic module operable to apply the at least one predictive model to the patient data to determine at least one risk score associated the at least one medical condition and identify at least one high-risk patient; a data presentation module operable to present notification and information to an intervention coordination team about the identified at least one high-risk patient; and an artificial intelligence tuning module adapted to automatically adjust parameters in the predictive model in response to trends in the patient data.

US Patent:

61839663, Feb 6, 2001

Filed:

Jan 22, 1999

Appl. No.:

9/235614

Inventors:

Donald M. Gray - Richardson TX
Christopher L. Clark - Plano TX

Assignee:

Board of Regents, University of Texas System - Dallas TX

International Classification:

C12Q 168

US Classification:

435 6

Abstract:

The invention provides methods of identifying a nucleic acid molecule having a sequence capable of targeting a gene of interest, and hence nucleic acid molecules useful in gene theraphy and disease treatment. A system and method for selecting antisense DNA oligonucleotide sequences that will form the most stable DNA:RNA hybrids within a given target mRNA sequence is provided. An apparatus capable of identifying a subject nucleic acid sequence capable of targeting a gene of interest is further provided. The apparatus includes the use of a software program and a computing unit. Methods for controlling gene expression are also provided.