Novel bioabsorbable polymeric blends are disclosed. The blends have a first component that is a polylactide polymers or a copolymer of lactide and glycolide and a second component that is poly(p-dioxanone) polymer. The novel polymeric blends provide medical devices having dimensional stability. Also disclosed are novel bioabsorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.
Readily Absorbable Copolymer Compositions For High-Strength Sutures Having Enhanced Strength Retention Post-Implantation
- Somerville NJ, US Christopher DeFelice - Springfield NJ, US Sasa Andjelic - Nanuet NY, US Brian M. Kelly - Ringoes NJ, US Marc Wisnudel - Millburn NJ, US Daniel Steiger - Basking Ridge NJ, US Gaoyuan Gavin Chen - Hillsborough NJ, US
Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
Christopher DeFelice - Verona NJ, US Matthew DeFelice - New Egypt NJ, US
International Classification:
A47G 9/10
Abstract:
Disclosed herein are devices and methods to continuously adjust pillow compression and firmness. In some aspects, the devices include at least one cord configured to an adjusting fixture, wherein the at least one cord comprises a plurality of cord segments that extend outward from the adjusting fixture, wherein at least one cord segment of the plurality of cord segments is configured to a pillow. Methods of use and manufacturing also are provided.
Readily Absorbable Copolymer Compositions For High Strength Sutures Having Enhanced Strength Retention Post-Implantation
- Somerville NJ, US Christopher DeFelice - Springfield NJ, US Sasa Andjelic - Nanuet NY, US Brian M. Kelly - Ringoes NJ, US Marc Wisnudel - Millburn NJ, US Daniel Steiger - Basking Ridge NJ, US Gaoyuan Gavin Chen - Hillsborough NJ, US
Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.
Absorbable Polymeric Blend Compositions Based On Copolymers Prepared From Mono- And Di-Functional Polymerization Initiators, Processing Methods, And Medical Devices Therefrom
- Somerville NJ, US Dennis D. Jamiolkowski - Long Valley NJ, US Brian M. Kelly - Ringoes NJ, US Christopher DeFelice - Springfield NJ, US Daniel Steiger - Basking Ridge NJ, US
International Classification:
A61L 31/04 C08L 67/00 A61L 31/14
Abstract:
Novel absorbable polymeric blends made from components wherein at least one of the components is synthesized using mixtures of mono- and di-functional initiators are disclosed. The blends have a first component that is a polylactide polymer or a copolymer of lactide and glycolide and a second component that is either poly(p-dioxanone) homopolymer, or a poly(p-dioxanone-co-glycolide) copolymer. The novel polymeric blends provide medical devices having dimensional stability. Also disclosed are novel absorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.
Absorbable Bimodal Polymeric Blend Compositions, Processing Methods, And Medical Devices
- Somerville NJ, US Sasa Andjelic - Nanuet NY, US Brian M. Kelly - Ringoes NJ, US Christopher DeFelice - Springfield NJ, US
International Classification:
C08L 67/04 A61L 31/14 A61L 31/04
Abstract:
Novel absorbable polymeric blends having bimodal molecular weight distribution are disclosed. The bimodal blends have a first component that is a polylactide polymer or a copolymer of lactide and glycolide having a bimodal molecular weight distribution, and a second component that is a poly(p-dioxanone) polymer of unimodal or bimodal molecular weight distribution. Alternately, the bimodal blends have a first component that is a polylactide polymer or a copolymer of lactide and glycolide having a unimodal molecular weight distribution, and a second component that is a poly(p-dioxanone) polymer of bimodal molecular weight distribution. The novel polymeric bimodal molecular weight blends provide medical devices having improved dimensional stability. Also disclosed are novel absorbable medical devices made from these novel bimodal polymer blends, as well as novel methods of manufacture.
Absorbable Polymeric Blend Compositions With Precisely Controllable Absorption Rates, Processing Methods, And Dimensionally Stable Medical Devices Therefrom
- Somerville NJ, US Daniel Steiger - Basking Ridge NJ, US Brian M. Kelly - Ringoes NJ, US Christopher DeFelice - Springfield NJ, US Sasa Andjelic - Nanuet NY, US Modesto Erneta - Princeton Junction NJ, US
International Classification:
A61L 31/04 A61L 31/14
US Classification:
525411
Abstract:
Novel absorbable polymeric blends are disclosed. The blends have a first absorbable polymer type that is a polylactide polymer or a copolymer of lactide and glycolide and a second absorbable polymer type that is poly(p-dioxanone), wherein the first absorbable polymer type or the second absorbable polymer type or the first absorbable polymer type and the second absorbable polymer type additionally comprise a first polymeric component and a second polymeric component. The first polymeric component has a higher weight average molecular weight than the second polymeric component and at least one of said components is at least partially end-capped by a carboxylic acid. The novel polymeric blends are useful for manufacturing medical devices having dimensional stability, having engineered degradation and breaking strength retention in vivo. Also disclosed are novel absorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.
Resumes
Founder / Chief Product Officer At Mozzo Analytics, Co-Owner At Wi-Design, Inc.
Founder / Chief Product Officer at Mozzo Analytics, Co-owner / Lead Developer at Wi-Design, Inc
Location:
Greater Philadelphia Area
Industry:
Information Technology and Services
Work:
Mozzo Analytics - Syracuse, New York and Philadelphia, PA since 2011
Founder / Chief Product Officer
Wi-Design, Inc - Philadelphia, PA since Jul 2008
Co-owner / Lead Developer
Electronic Data Systems - Woodcrest, NJ Apr 2005 - Jun 2008
Job Execution Specialist
2003-2005 Towers Perrin - Philadelphia, PA Jan 2003 - May 2005
Job Execution Specialist
Carnegie Medal Carnegie Hero Fund "To recognize persons who perform acts of heroism in civilian life in the United States..."
Carnegie Hero Fund Mission: http://carnegiehero.org/about-the-fund/mission/
Press release: http://carnegiehero.org/awardees/#13
Christopher Defelice 2004 graduate of Patrick Henry High School in San diego, CA is on Memory Lane. Get caught up with Christopher and other high school alumni