Christopher Wilson Delaney

US Patent:

20210246411, Aug 12, 2021

Filed:

Apr 29, 2021

Appl. No.:

17/244447

Inventors:

- Clemson SC, US
CHRISTOPHER DELANEY - WINSTON-SALEM NC, US
RICHARD PASCAL, III - CHAPIN SC, US
DAN SIMIONESCU - PENDLETON SC, US
AGNETA SIMIONESCU - PENDLETON SC, US

International Classification:

C12M 1/34
C12M 1/00
C12M 1/42
C12M 3/00

Abstract:

Bioreactors and components of bioreactors are described as may be beneficially utilized in development and conditioning of cellular materials for study or implant. The bioreactors are modular, and components of the bioreactors can be easily assembled with alternatives provided to develop specific, predetermined conditioning environments for cellular materials (e.g., implantable tissue). By selection of one of multiple alternative compliance chambers, a bioreactor can be utilized to condition tissue in a low-pressure circuit (e.g., a pulmonary heart circuit), and by utilization of an alternative compliance chamber, the bioreactor can instead condition tissue in a high-pressure circuit (e.g., an aortic heart circuit).

US Patent:

20160024452, Jan 28, 2016

Filed:

Jul 23, 2015

Appl. No.:

14/807357

Inventors:

- Clemson SC, US
Christopher Delaney - Winston-Salem NC, US
Richard Pascal, III - Chapin SC, US
Dan Simionescu - Pendleton SC, US
Agneta Simionescu - Pendleton SC, US

International Classification:

C12M 1/02
C12M 1/34

Abstract:

Bioreactors and components of bioreactors are described as may be beneficially utilized in development and conditioning of cellular materials for study or implant. The bioreactors are modular and components of the bioreactors can be easily assembled with alternatives provided to develop specific, predetermined conditioning environments for cellular materials (e.g., implantable tissue). By selection of one of multiple alternative compliance chambers, a bioreactor can be utilized to condition tissue in a low pressure circuit (e.g., a pulmonary heart circuit), and by utilization of an alternative compliance chamber, the bioreactor can instead condition tissue in a high pressure circuit (e.g., an aortic heart circuit).