Christopher E Harvey

US Patent:

6500272, Dec 31, 2002

Filed:

Jan 22, 2001

Appl. No.:

09/767039

Inventors:

Scott R. Cline - Enosburg Falls VT
Christopher E. Harvey - Jericho VT
Willi O. Kalvaitis - West Chazy NY
Davis H. Moquin - Plattsburgh NY

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

B08B 504

US Classification:

134 21, 15301, 15345

Abstract:

A purge/vent system ( ) for and method of purging/venting a brush arm bearing. The purge/vent system includes a driven mechanism ( ) and a support member ( ) having a first cavity ( ) for containing the driven mechanism. A gas supply system ( ) is in fluid communication with the first cavity proximate the upper end ( ) of the driven mechanism, and an evacuation system ( ) is in fluid communication with the first cavity proximate the lower end ( ) of the driven mechanism. In operation, the gas supply system supplies a gas to the first chamber and the evacuation system draws the gas from the first chamber. As the evacuation system draws the gas from the first chamber, the gas is drawn across and/or through the driven mechanism to keep the driven mechanism dry and/or remove foreign material from the first chamber.

US Patent:

20140004112, Jan 2, 2014

Filed:

Sep 12, 2013

Appl. No.:

14/025573

Inventors:

Bettina Franz - Cambridge, GB
Glenn Dranoff - Sudbury MA, US
F. Stephen Hodi - Framingham MA, US
Christopher Harvey - Boston MA, US

Assignee:

Dana-Farber Cancer Institute, Inc. - Boston MA

International Classification:

C07K 16/28
A61K 45/06
A61K 39/395

US Classification:

4241331, 5303891, 5303873, 4241721

Abstract:

The present disclosure provides, in part, compositions comprising peptides immunospecifically binds to defined binding partners, wherein the peptides comprise at least complementarity determining regions relating to the complementarity regions shown in Table 1.

US Patent:

20220281978, Sep 8, 2022

Filed:

Dec 14, 2021

Appl. No.:

17/550276

Inventors:

- Cambridge MA, US
Deborah Law - Cambridge MA, US
Christopher Harvey - Boston MA, US
Elizabeth G. Trehu - Cambridge MA, US
Lauren Pepper MacKenzie - Cambridge MA, US
Amit Deshpande - Cambridge MA, US
Jennifer S. Michaelson - Brighton MA, US
Igor Feldman - Jamaica Plain MA, US
Sriram Sathyanarayanan - Lexington MA, US

Assignee:

Jounce Therapeutics, Inc. - Cambridge MA

International Classification:

C07K 16/28
A61P 35/00
A61K 39/00
A61K 39/395
C12Q 1/6886
G01N 33/68

Abstract:

Methods of treating cancer with particular doses of anti-ICOS antibodies are provided.

US Patent:

20210355222, Nov 18, 2021

Filed:

Oct 25, 2019

Appl. No.:

17/286104

Inventors:

- Cambridge MA, US
Christopher Harvey - Boston MA, US
Deborah Law - Cambridge MA, US
Amanda Hanson - Cambridge MA, US

Assignee:

Jounce Therapeutics, Inc. - Cambridge MA

International Classification:

C07K 16/28
A61K 45/06
G01N 33/50
G01N 33/68
A61P 35/00

Abstract:

The present disclosure provides methods of treating cancer and methods for selecting treatment approaches for cancer.

US Patent:

20210340256, Nov 4, 2021

Filed:

Feb 5, 2021

Appl. No.:

17/168544

Inventors:

- Cambridge MA, US
Igor Feldman - Jamaica Plain MA, US
Christopher Harvey - Boston MA, US
Sriram Sathyanarayanan - Lexington MA, US
Heather Hirsch - Brookline MA, US
Lauren Pepper MacKenzie - Cambridge MA, US
Amit Deshpande - Cambridge MA, US
Stephen Sazinsky - Melrose MA, US
Jennifer S. Michaelson - Brighton MA, US
Kutlu Goksu Elpek - Arlington MA, US

Assignee:

Jounce Therapeutics, Inc. - Cambridge MA

International Classification:

C07K 16/28
C12Q 1/6886
A61P 35/00
A61K 39/00
A61K 39/395

Abstract:

Gene expression signatures correlating to ICOS expression levels are provided. Methods of treatment comprising determining ICOS expression levels using gene signatures in patients and administering anti-ICOS antibodies are also provided.

US Patent:

20200024351, Jan 23, 2020

Filed:

Apr 2, 2018

Appl. No.:

16/497937

Inventors:

- Cambridge MA, US
Deborah Law - Cambridge MA, US
Christopher Harvey - Boston MA, US
Beth G. Trehu - Cambridge MA, US
Lauren Pepper MacKenzie - Cambridge MA, US
Amit Deshpande - Cambridge MA, US
Jennifer S. Michaelson - Brighton MA, US
Igor Feldman - Jamaica Plain MA, US
Sriram Sathyanarayanan - Lexington MA, US

Assignee:

Jounce Therapeutics, Inc. - Cambridge MA

International Classification:

C07K 16/28
A61P 35/00
C12Q 1/6886
G01N 33/68
A61K 39/00
A61K 39/395

Abstract:

Methods of treating cancer with particular doses of anti-ICOS antibodies are provided.

US Patent:

20180371091, Dec 27, 2018

Filed:

Oct 21, 2016

Appl. No.:

15/767172

Inventors:

- Cambridge MA, US
Igor Feldman - Jamaica Planin MA, US
Christopher Harvey - Boston MA, US
Sriram Sathyanarayanan - Lexington MA, US
Heather Hirsch - Brookline MA, US
Lauren Pepper MacKenzie - Cambridge MA, US
Amit Deshpande - Cambridge MA, US
Stephen Sazinsky - Melrose MA, US
Jennifer S. Michaelson - Brighton MA, US
Kutlu Gosku Elpek - Arlington MA, US

Assignee:

Jounce Therapeutics, Inc. - Cambridge MA

International Classification:

C07K 16/28
C12Q 1/6886
A61P 35/00

Abstract:

Gene expression signatures correlating to ICOS expression levels are provided. Methods of treatment comprising determining ICOS expression levels using gene signatures in patients and administering anti-ICOS antibodies are also provided.

US Patent:

20170022275, Jan 26, 2017

Filed:

Dec 5, 2014

Appl. No.:

15/100060

Inventors:

- Boston MA, US
Glenn DRANOFF - Sudbury MA, US
F. Stephen HODI - Framingham MA, US
Bettina FRANZ - Orem UT, US
Christopher HARVEY - Boston MA, US

International Classification:

C07K 16/28
A61K 45/06
A61K 39/395

Abstract:

The present disclosure provides, in part, compositions comprising peptides immunospecifically binds to MHC class I polypeptide-related sequence A (MICA).