Christopher John Ott

US Patent:

20170284737, Oct 5, 2017

Filed:

Jun 19, 2017

Appl. No.:

15/626301

Inventors:

- Allentown PA, US
Yang Liu - Springfield NJ, US
Gowri Krishnamurthy - Sellersville PA, US
Christopher Michael Ott - Macungie PA, US
Mark Julian Roberts - Kempton PA, US

Assignee:

AIR PRODUCTS AND CHEMICALS, INC. - Allentown PA

International Classification:

F25J 3/06
F25J 1/02
F25J 3/02
F25J 1/00

Abstract:

A method and apparatus for liquefying a natural gas feed stream and removing nitrogen therefrom to produce a nitrogen-depleted LNG product, in which a natural gas feed stream is fed into the warm end of a main heat exchanger, cooled and at least partially liquefied, withdrawn from an intermediate location of the main heat exchanger and separated to form a nitrogen-enriched natural gas vapor stream and a nitrogen-depleted natural gas liquid stream, the liquid and vapor streams being reintroduced into an intermediate location of the main heat exchanger and further cooled in parallel to form a first LNG stream and a first at least partially liquefied nitrogen-enriched natural gas stream, respectively.

US Patent:

20160024495, Jan 28, 2016

Filed:

Feb 15, 2013

Appl. No.:

14/378698

Inventors:

- Piscataway NJ, US
- Boston MA, US
Zhengxing Qu - Warren NJ, US
Lee Greenberger - Montclair NJ, US
Christopher Ott - Boston MA, US
James Elliott Bradner - Boston MA, US

International Classification:

C12N 15/113

Abstract:

The disclosure relates to oligonucleotide compounds (oligomers) that target Myc mRNA in a cell, leading to reduced expression of Myc. Reduction of Myc expression is beneficial for the treatment of certain disorders, such as hyperproliferative disorders (e.g., cancer). The disclosure provides therapeutic compositions comprising oligomers and methods for modulating the expression of Myc using said oligomers, including methods of treatment.