Christopher K Rose

US Patent:

6804574, Oct 12, 2004

Filed:

Oct 8, 2002

Appl. No.:

10/267007

Inventors:

Xinbing Liu - Acton MA
Chen-Hsiung Cheng - Chelmsford MA
John Cronin - Milton VT
Nancy Edwards - Essex Junction VT
Christopher Rose - Essex Junction VT

Assignee:

Matsushita Electric Industrial Co., Ltd. - Osaka

International Classification:

G06F 1900

US Classification:

700166, 700180

Abstract:

A method of determining compatibility of user input parameters for use with a laser drilling system includes providing compatibility data characteristic of a plurality of laser drilling operations, receiving input parameters characteristic of a desired laser drilling operation, and comparing the input parameters to the compatibility data, thereby determining whether the input parameters are incompatible.

US Patent:

20190310264, Oct 10, 2019

Filed:

Jun 1, 2017

Appl. No.:

16/306686

Inventors:

- Cambridge MA, US
Brian K. Erickson - Brookline MA, US
Christopher Michael Rose - Fremont CA, US
Steven P. Gygi - Foxborough MA, US

Assignee:

President and Fellows of Harvard College - Cambridge MA

International Classification:

G01N 33/68

Abstract:

Described herein is a kit of materials prepared for assays that involve determining relative abundance and/or absolute abundance of various targeted peptides. The kit may comprise trigger versions of target peptides with masses offset from the respective target peptides by predetermined and known amounts. The trigger peptides may be present in amounts that may be readily detected via a mass spectrometry analysis. When mixed with samples that are analyzed, detection of the trigger peptides indicates where in the mass-spectrometer output the target peptide may be found. The kit may include a predetermined amount of synthetic versions of one or more of the target peptides. A measured relative abundance of this synthetic peptide relative to that of the target peptides yields an absolute quantitative value of the target peptide. Also disclosed is a method of preparing a plurality of samples to be submitted for mass spectrometer analysis in parallel.