Christopher H Simons

US Patent:

8187822, May 29, 2012

Filed:

Mar 27, 2008

Appl. No.:

12/593155

Inventors:

Nicole Erna Irene Brune - San Diego CA, US
Jay Patrick Slack - Loveland OH, US
Ioana Maria Ungureanu - Cincinnati OH, US
Kimberley Gray - Loveland OH, US
Christopher Todd Simons - Wyoming OH, US
Jenny Ellen Evans Pennimpede - Cincinnati OH, US

Assignee:

Givaudan S.A.

International Classification:

G01N 33/567
C07K 14/705

US Classification:

435 72, 435 71, 435 721, 436501

Abstract:

Sucralose-binding TAS2R bitter taste receptors have been identified. Novel methods to identify modulators and in particular inhibitors to the bitter taste of sucralose, and an inhibitor, are provided.

US Patent:

8409649, Apr 2, 2013

Filed:

Mar 27, 2008

Appl. No.:

12/593114

Inventors:

Ioana Maria Ungureanu - Cincinnati OH, US
Nicole Erna Irene Brune - San Diego CA, US
Jay Patrick Slack - Loveland OH, US
Kimberley Gray - Loveland OH, US
Christopher Todd Simons - Wyoming OH, US
Jenny Ellen Evans Pennimpede - Cincinnati OH, US

Assignee:

Givaudan S.A. - Bernier

International Classification:

A23L 2/56
A23L 1/236
A23L 1/22
A61K 9/68
C07C 61/08
A23G 4/06

US Classification:

426534, 426650, 426548, 426590, 424 48, 562506, 562400

Abstract:

Disclosed are compounds that block off-notes in consumables and methods of blocking off-notes in consumables including off-notes provided by artificial sweeteners including aspartame, saccharin, acesulfame K (Acesulfame potassium), sucralose and cyclamate; and including stevioside, swingle extract, glyccerhizin, perillartine, naringin dihydrochalcone, neohesperidine dihydrochalcone, mogroside V, rubusoside, rubus extract, and rebaudioside A.

US Patent:

8597896, Dec 3, 2013

Filed:

May 26, 2012

Appl. No.:

13/481797

Inventors:

Nicole Erna Irene Brune - San Diego CA, US
Jay Patrick Slack - Loveland OH, US
Ioana Maria Ungureanu - Cincinnati OH, US
Kimberley Gray - Loveland OH, US
Christopher Todd Simons - Wyoming OH, US
Jenny Ellen Evans Pennimpede - Cincinnati OH, US

Assignee:

Givaudan S.A.

International Classification:

G01N 33/567
C07K 14/705

US Classification:

435 71, 435 721, 436501

Abstract:

Sucralose-binding TAS2R bitter taste receptors have been identified. Novel methods to identify modulators and in particular inhibitors to the bitter taste of sucralose, and an inhibitor, are provided.

US Patent:

20090311686, Dec 17, 2009

Filed:

Apr 20, 2007

Appl. No.:

12/297851

Inventors:

Jay Patrick Slack - Loveland OH, US
Christopher Todd Simons - Wyoming OH, US
Chad Allen Hansen - Kings Mills OH, US

Assignee:

GIVAUDAN SA - Vernier

International Classification:

C12Q 1/68
G01N 33/53
G01N 33/569

US Classification:

435 6, 435 72, 435 732, 435 721, 435 731

Abstract:

We have discovered a method to enhance sweetness comprising the use of a sweetener at a sub- to near-threshold concentration which is used in combination with a suprathreshold concentration of another sweetener. The sweetener used at the near-threshold concentration is selected based on its likely binding site in the human sweet taste receptor. The invention relates to the identification of agents that can modulate the taste response in humans (such as sweet taste enhancers) through assays based on a novel sweet receptor protein, heterologous expression systems containing nucleic acid constructs forming said novel sweet receptor protein, and the use of the novel sweet receptor protein in screening.

US Patent:

20100092638, Apr 15, 2010

Filed:

Oct 22, 2007

Appl. No.:

12/444754

Inventors:

Chad Allen Hansen - Kings Mills OH, US
Jay Patrick Slack - Loveland OH, US
Christopher Todd Simons - Wyoming OH, US

International Classification:

A23L 1/236
A23L 2/60

US Classification:

426548

Abstract:

Disclosed are sweetened consumables and methods of forming said sweetened consumables that comprise certain sweeteners and at least one sweetness enhancer in a concentration near its sweetness detection threshold. The sweeteners include sucrose, fructose, glucose, high fructose corn syrup, corn syrup, xylose, arabinose, rhamnose, erythritol, xylitol, mannitol, sorbitol, inositol, acesulfame potassium, aspartame, neotame, sucralose, saccharine, or combinations thereof. The sweetness enhancer is selected from naringin dihydrochalcone, mogroside V, swingle extract, rubusoside, rubus extract, rebaudioside, and stevioside.

US Patent:

20100178389, Jul 15, 2010

Filed:

Jun 6, 2008

Appl. No.:

12/663321

Inventors:

Zhonghua Jia - Cincinnati OH, US
Xiaogen Yang - West Chester OH, US
Chad Allen Hansen - Kings Mills OH, US
Charles Benjamin Naman - Cincinnati OH, US
Christopher Todd Simons - Wyoming OH, US
Jay Patrick Slack - Loveland OH, US
Kimberley Gray - Loveland OH, US

Assignee:

GIVAUDAN SA - Vernier

International Classification:

A23L 1/22
A23L 1/09
A23L 2/60
A23L 1/236

US Classification:

426 67, 426548, 426 66, 426321

Abstract:

Disclosed are sweetened consumables and methods of forming said sweetened consumables that comprise certain sweeteners and a compound of formula (1), wherein Ris selected from the group consisting of OH and OCH, and Ris selected from the group consisting of H and OH, Rand Rcomprise at least one OH group, and when Ris OH then Ris H (trilobtain), and when Ris OCHthen Ris OH (HDG), in a concentration near its sweetness detection threshold. The sweeteners include sucrose, fructose, glucose, high fructose corn syrup, corn syrup, xylose, arabinose, rhamnose, erythritol, xylitol, mannitol, sorbitol, inositol, acesulfame potassium, aspartame, neotame, sucralose, saccharine, or combinations thereof.

US Patent:

20100311786, Dec 9, 2010

Filed:

Jul 28, 2008

Appl. No.:

12/669393

Inventors:

Ioana Maria Ungureanu - Cincinnati OH, US
Nicole Erna Irene Brune - Dan Diego CA, US
Jay Patrick Slack - Loveland OH, US
Kimberley Gray - Loveland OH, US
Christopher Todd Simons - Wyoming OH, US
Jenny Ellen Evans Pennimpede - Cincinnati OH, US

International Classification:

A61K 31/4748
C07C 61/06
C07C 61/08
A61K 47/12
A61K 31/445
A61P 11/14
A61P 29/00
A23L 1/226
A23G 4/06
A23L 1/302

US Classification:

514289, 562503, 562400, 514784, 514327, 426538, 426 3, 426 72, 426442

Abstract:

Disclosed are compounds that block off-notes in consumables and methods of blocking off-notes in consumables including off-notes provided by sweeteners such as stevioside, swingle extract, glyccerhizin, perillartine, naringin dihydrochalcone, neohesperidine dihydrochalcone, mogroside V, rubusoside, rubus extract, and rebaudioside A, and artificial sweeteners such as aspartame, saccharin, acesulfame K (Acesulfame potassium), sucralose and cyclamate.

US Patent:

20120308706, Dec 6, 2012

Filed:

Aug 14, 2012

Appl. No.:

13/585009

Inventors:

Chad Allen HANSEN - Kings Mills OH, US
Jay Patrick Slack - Loveland OH, US
Christopher Todd Simons - Wyoming OH, US

International Classification:

A23L 1/22
A23L 2/60
A23L 1/236

US Classification:

426548, 426658, 426590, 426442

Abstract:

Disclosed are sweetened consumables and methods of forming said sweetened consumables that comprise certain sweeteners and at least one sweetness enhancer in a concentration near its sweetness detection threshold. The sweeteners include sucrose, fructose, glucose, high fructose corn syrup, corn syrup, xylose, arabinose, rhamnose, erythritol, xylitol, mannitol, sorbitol, inositol, acesulfame potassium, aspartame, neotame, sucralose, saccharine, or combinations thereof. The sweetness enhancer is selected from naringin dihydrochalcone, mogroside V, swingle extract, rubusoside, rubus extract, rebaudioside, and stevioside.