Chung L Chang

US Patent:

6820095, Nov 16, 2004

Filed:

Apr 16, 2001

Appl. No.:

09/834658

Inventors:

Sofia Yeung - Union City CA
Chung Chang - San Jose CA

Assignee:

Oracle International Corporation - Redwood Shores CA

International Classification:

G06F 1730

US Classification:

707200, 707205, 711173

Abstract:

An object, such as a relational database table, is partitioned into a plurality of subsets. Selected subsets, e. g. partitions, of the object are exported into a dump file, identifying each exported subset of data by writing a marker in the dump file. Selected subsets are imported from the dump file, by determining whether the marker in the dump file corresponds to the selected subsets, then conditionally importing the data associated with the marker. Objects are repartitioned by exporting the some of the subsets, reconfiguring the object, and importing the exported subsets back into the object.

US Patent:

7604800, Oct 20, 2009

Filed:

May 10, 2005

Appl. No.:

11/125837

Inventors:

Rong-Hwa Lin - Taipei, TW
Chung Nan Chang - Foster City CA, US
Pei-Jiun Chen - Taipei, TW
Chiu-Chen Huang - Taipei, TW

Assignee:

AbGenomics Coöperatief U.A. - Amsterdam

International Classification:

A61K 39/395
C07K 16/28

US Classification:

4241541, 4241301, 4241331, 4241411, 4241431, 4241441, 4241521, 4241531, 4241721, 4241731, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 53038875

Abstract:

Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject.

US Patent:

8287871, Oct 16, 2012

Filed:

Mar 6, 2009

Appl. No.:

12/399484

Inventors:

Rong-Hwa Lin - Taipei, TW
Chung Nan Chang - Foster City CA, US
Pei-Jiun Chen - Taipei, TW
Chiu-Chen Huang - Taipei, TW

Assignee:

AbGenomics Cooperatief U.A. - Amsterdam

International Classification:

A61K 39/395
C07K 16/28

US Classification:

4241541, 4241301, 4241331, 4241411, 4241431, 4241441, 4241521, 4241531, 4241721, 4241731, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 53038875

Abstract:

Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject.

US Patent:

8361472, Jan 29, 2013

Filed:

Aug 17, 2010

Appl. No.:

12/858110

Inventors:

Chung Nan Chang - Foster City CA, US
Pei-Jiun Chen - Taipei, TW
Chiu-Chen Huang - Taipei, TW

Assignee:

AbGenomics Cooperatief U.A. - Amsterdam

International Classification:

A61K 39/395
C07K 16/28

US Classification:

4241541, 4241301, 4241331, 4241411, 4241431, 4241441, 4241521, 4241531, 4241721, 4241731, 5303871, 5303873, 5303881, 5303882, 53038822, 5303887, 53038873, 53038875

Abstract:

Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject.

US Patent:

8628775, Jan 14, 2014

Filed:

Sep 18, 2009

Appl. No.:

12/562515

Inventors:

Chung Nan Chang - Foster City CA, US

Assignee:

AbGenomics Cooperatief U.A. - Cm Amsterdam Zuidoost

International Classification:

A61K 38/17
C07K 14/435

US Classification:

4241341, 4241921, 514 122, 514 209, 530350, 5303873

Abstract:

Multimeric compounds that bind to P-Selectin Glycoprotein 1 (PSGL-1) on the surface of T cells or natural killer (NK) cells can be used to induce T cell or NK cell depletion and/or to induce T cell or NK cell apoptosis. The multimeric compounds and methods of the invention can be used to control unwanted T cell- or NK cell-mediated immune responses in conditions such as inflammatory diseases, autoimmune diseases, transplant rejection, and allergic diseases.

US Patent:

20040116333, Jun 17, 2004

Filed:

Sep 15, 2003

Appl. No.:

10/662906

Inventors:

Rong-Hwa Lin - Taipei, TW
Chung Chang - Foster City CA, US

International Classification:

A61K038/17
A61K038/16

US Classification:

514/008000

Abstract:

Multimeric compounds that bind to P-Selectin Glycoprotein 1 (PSGL-1) on the surface of T cells or natural killer (NK) cells can be used to induce T cell or NK cell depletion and/or to induce T cell or NK cell apoptosis. The multimeric compounds and methods of the invention can be used to control unwanted T cell- or NK cell-mediated immune responses in conditions such as inflammatory diseases, autoimmune diseases, transplant rejection, and allergic diseases.

US Patent:

20060003940, Jan 5, 2006

Filed:

May 11, 2005

Appl. No.:

11/127804

Inventors:

Rong-Hwa Lin - Taipei, TW
Chung Chang - Foster City CA, US

International Classification:

A61K 38/10
A61K 38/08
C07K 7/08
C07K 7/06

US Classification:

514014000, 514017000, 514016000, 514015000, 530328000, 530329000, 530330000

Abstract:

Cell death-inducing epitopes and polypeptides containing same. Also disclosed are compounds for inducing death of activated T-cells, a method of producing antibodies to the epitopes, a method of identifying compounds that bind to the epitopes, a method of inducing death of activated T-cells, and pharmaceutical compositions containing the compounds.

US Patent:

20090198044, Aug 6, 2009

Filed:

Mar 6, 2009

Appl. No.:

12/399516

Inventors:

Rong-Hwa Lin - Taipei, TW
Chung Nan Chang - Foster City CA, US
Pei-Jiun Chen - Taipei, TW
Chiu-Chen Huang - Taipei, TW

Assignee:

AbGenomics Cooperatief U.A. - Amsterdam

International Classification:

C07K 16/18

US Classification:

5303873, 5303879

Abstract:

Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject.