Chung Yiu Lee

US Patent:

6874699, Apr 5, 2005

Filed:

Oct 15, 2002

Appl. No.:

10/271250

Inventors:

Bradley James Larson - Madison WI, US
Chung Hoon Lee - Ithaca NY, US
Amit Lal - Ithaca NY, US
Max G. Lagally - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

B05B001/08

US Classification:

2391021, 2391022, 239 86, 2395891, 422100, 422930, 73 174, 7386332, 7386401, 7386422, 347 46, 347 47

Abstract:

Devices and methods for depositing fluids on substrates in patterns of spots, lines, or other features use a nozzle, which is preferably configured similarly to a micropipette, having a piezoelectric crystal or other ultrasonic actuator coupled to one of its sides. The nozzle may be charged via capillary action by dipping it into a well containing the fluid to be deposited, and may then be positioned over a desired area of a substrate, at which point activation of the ultrasonic actuator at ultrasonic frequencies will eject the fluid onto the substrate. The needle may subsequently be dipped into a well of rinsing fluid for cleaning. Spots or lines on the order of 5 micrometers width may be generated, making the invention particularly suitable for use in biological applications such as microarray production and in microelectronics applications such as the printing of organic circuitry.

US Patent:

7467751, Dec 23, 2008

Filed:

Feb 22, 2005

Appl. No.:

11/064226

Inventors:

Bradley James Larson - Madison WI, US
Chung Hoon Lee - Ithaca NY, US
Amit Lal - Ithaca NY, US
Max G. Lagally - Madison WI, US

Assignee:

Wisconsin Alumni Research Foundation - Madison WI

International Classification:

B05B 1/08

US Classification:

2391021, 2391022, 239 86, 2395891, 422100, 422930, 73 174, 7386301, 7386422, 347 46, 347 47

Abstract:

Devices and methods for depositing fluids on substrates in patterns of spots, lines, or other features use a nozzle, which is preferably configured similarly to a micropipette, having a piezoelectric crystal or other ultrasonic actuator coupled to one of its sides. The nozzle may be charged via capillary action by dipping it into a well containing the fluid to be deposited, and may then be positioned over a desired area of a substrate, at which point activation of the ultrasonic actuator at ultrasonic frequencies will eject the fluid onto the substrate. The needle may subsequently be dipped into a well of rinsing fluid for cleaning. Spots or lines on the order of 5 micrometers width may be generated, making the invention particularly suitable for use in biological applications such as microarray production and in microelectronics applications such as the printing of organic circuitry.