Dusan Pavcnik - Portland OR, US Clay D. Fette - Lebanon IN, US Jason A. Mead - Plainfield IN, US Joseph F. Obermiller - West Lafayette IN, US Fred T. Parker - Unionville IN, US
Assignee:
Oregon Health & Science University - Portland OR Cook Incorporated - Bloomington IN Cook Biotech, Inc. - West Lafayaette IN
International Classification:
A61F 2/06
US Classification:
623 113, 623 116
Abstract:
A stent tissue graft prosthesis () for repairing, excluding and/or reinforcing a vessel, duct and the like in a patient. The prosthesis includes an inner expandable stent () of which a tissue graft () and preferably a multilayered tissue construct () is disposed thereon for application to the host tissue of a vessel, duct and the like. The tissue construct includes an extracellular matrix material () such as small intestine submucosa () for remodeling the host tissue into the prosthesis. The prosthesis further includes an outer tubular member () such as an outer expandable stent () for retaining the tissue graft on the inner stent. The ends of the inner and outer stents are coincident with or extend beyond the ends of the tissue graft to prevent eversion or fold back of the tissue graft during withdrawal of a delivery catheter in a placement procedure.
Dusan Pavcnik - Portland OR, US John Kaufman - Lake Oswego OR, US Clay D. Fette - Lebanon IN, US
Assignee:
Cook Biotech Incorporated - West Lafayette IN Oregon Health Science University - Portland OR
International Classification:
A61B 17/08
US Classification:
606213, 623 2372
Abstract:
An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc. , comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e. g. , an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.
Dusan Pavcnik - Portland OR, US John Kaufman - Lake Oswego OR, US Clay D. Fette - Lebanon IN, US
Assignee:
Oregon Health Science University - Portland OR Cook Biotech Incorporated - West Lafayette IN Cook Medical Technologies LLC - Bloomington IN
International Classification:
A61B 17/08
US Classification:
606213, 623 2372
Abstract:
An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc. , comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e. g. , an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.
Miles Grody - Columbia MD, US Clay Fette - Severna Park MD, US
Assignee:
ACell, Inc. - Columbia MD
International Classification:
A61K 35/12 A61K 35/32
US Classification:
424572, 424574, 424443, 424444
Abstract:
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
Brian Bates - Bloomington IN, US Clay Fette - Lebanon IN, US Ram Paul - Bloomington IN, US Paul Amarant - Bloomington IN, US
Assignee:
COOK INCORPORATED - Bloomington IN COOK BIOTECH INCORPORATED - West Lafayette IN
International Classification:
A61F002/06 A61B017/08
US Classification:
606153000, 606151000, 623001150
Abstract:
An anastomosis device () for advantageously bridging an artery and a vein. The anastomosis device includes a tubular graft () with first and second ends (and ) and a longitudinal passageway extending longitudinally through the graft. The device further includes a first stent () disposed about the first end of the tubular graft and a second stent () disposed about the second end of the tubular graft. Each of the first and second stents has a plurality of hooks or barbs () pointed or releasable to the point toward the other end of the graft.
Dario Vitali - New Smyma Beach FL, US Rogelio Insignares - Miami FL, US Ken Roger - Casselbury FL, US Clay Fette - Palm Beach Gardens FL, US
International Classification:
A61M 5/158
US Classification:
604272
Abstract:
An optical safety trocar and method of use thereof, wherein a shield deploys to guard against accidental tip contact and potential injury therefrom, and wherein an optical tip facilitates visualization of the trocar advancement into a body cavity, such that the visualization not only precludes blind penetration in order to avoid inadvertently injurious positioning of the tip, but enables identification of any unintentional and otherwise undetectable damage.
Clay Fette - Severna Park MD, US Abram Janis - Columbia MD, US Benjamin Kibalo - Columbia MD, US
International Classification:
A61B 17/00
US Classification:
606213, 424484, 424 937
Abstract:
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
Compositions With Antiviral Activity And Related Methods
Compositions that include extracellular matrix (ECM) materials having antiviral activity and methods of use thereof are disclosed. The compositions may be administered to a subject in need thereof, e.g., subject having a viral infection or being suspected of having a viral infection. The virus may be an enveloped virus, such as a coronavirus.