An aqueous air foam comprising a non-crosslinked cellulose ether selected from C1–C3-alkyl celluloses, C1–C3-alkylhydroxy-C1–3-alkyl celluloses, hydroxy-C1–3-alkyl celluloses, or mixed hydroxy-C1–C3-alkyl celluloses, the foam having quality FQ of from 60 to 97 percent and the foam quality being defined as FQ (%)=(air volume+fluid volume)×100).
Paul J. Sheskey - Midland MI, US Colin M. Keary - Midland MI, US
Assignee:
Dow Global Technologies,Inc. - Midland MI
International Classification:
B05D 5/00
US Classification:
427 214, 4272133, 427242
Abstract:
A process for coating solid particles which comprises the steps of a) contacting a gas with a fluid composition comprising i) a polymer and ii) a liquid diluent to produce a foam, and b) contacting the produced foam with solid particles and agitating the particles to provide a coating on the solid particles.
The water dispersibility of water-soluble polymer particles can be improved by a method which comprises the following step: i) foaming a fluid composition comprising a compound A) having a weight average molecular weight of less than 10,000 or a water-insoluble polymer B) having a weight average molecular weight of at least 10,000; ii) contacting the produced foam with water-soluble polymer particles having a weight average molecular weight of at least 10,000; and iii) drying the particles, whereby the foam collapses during the contacting and/or drying step and the water-soluble polymer particles are encrusted with the compound having a weight average molecular weight of less than 10,000 or the water-insoluble polymer having a weight average molecular weight of at least 10,000.
Paul Sheskey - Midland MI, US Colin Keary - Midland MI, US
International Classification:
A61K009/14 A61K009/16 A61K009/50
US Classification:
424/489000, 424/493000
Abstract:
A process for dispersing a fluid in solid particles which comprises the steps of (a) contacting a gas with a fluid composition comprising (i) from 0.01 to 30 weight percent of a polymer and (ii) from 99.99 to 70 weight percent of a liquid diluent, based on the total weight of the polymer (i) and the liquid diluent (ii), to produce a foam, and (b) contacting the produce foam with solid particles of an average size of less than 2500 micrometers, the weight ratio between the foam and the solid particles being from 1:20 to 1:02. When the fluid composition comprises a binder, a granular material is produced which can be pressed to tablets.
Process For Dispersing A Fluid In A Mass Of Solid Particles
Paul Sheskey - Midland MI, US Colin Keary - Midland MI, US
International Classification:
A61K009/20
US Classification:
424464000, 264109000
Abstract:
A fluid is dispersed in a mass of solid particles in a process wherein a) a gas is contacted with a fluid composition comprising i) from 0.001 to 30 weight percent of a surfactant having a weight average molecular weight of up to 30000 and ii) from 99.999 to 70 weight percent of a liquid diluent, based on the total weight of the surfactant i) and the liquid diluent ii), and b) the produced foam is contacted with solid particles of an average size of less than 2500 micrometers, wherein a therapeutic agent is comprised in the fluid composition or in the mass of solid particles or both.
Haze-Free Cellulose Ether Capsules And Process For Making
Colin M. Keary - Midland MI Gary J. Schulz - Midland MI
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
C09D10126 C09D10128 C08B 1120 B28B 138
US Classification:
1061721
Abstract:
Disclosed is a cellulose ether composition having a low molecular weight cellulose ether of a viscosity of about 200 centipoise or less in a two percent aqueous solution at 20. degree. C. The composition has a sodium chloride content of about 0. 3 weight percent or less based upon the weight of the cellulose ether. The composition exhibits significantly reduced haze formation when in capsule form. Also disclosed is a process for making the composition.
In Situ, Liquid-Activated Film Coated Tablets And A Process For Making The Same
Tablets and other objects are film coated by including in the tablet a film-forming polymer that is activated upon contact with an activating amount of liquid. The film-forming polymer, e.g., a cellulosic ether, is homogeneously mixed with the other ingredients of the tablet, shaped into any desirable form, loaded into a conventional coating apparatus, and sprayed or foamed with an activating amount of fluid, e.g., water, alcohol, etc., and dried. This coating process eliminates potential problems such as spray nozzle clogging, inappropriate coating fluid viscosity, and the inability to properly atomize the coating fluid. This coating process does not impart any appreciable weight or thickness gain to the tablet.