Colleen J Kane

US Patent:

20110318353, Dec 29, 2011

Filed:

Mar 30, 2011

Appl. No.:

13/075241

Inventors:

Juan Carlos Almagro - Radnor PA, US
Patrick Branigan - Radnor PA, US
Colleen Kane - Radnor PA, US
William Strohl - Radnor PA, US
Susann Taudte - Radnor PA, US
Mark Tornetta - Radnor PA, US
John Wheeler - Radnor PA, US

International Classification:

A61K 39/395
C12N 15/13
C12N 15/63
A61P 29/00
C12N 1/21
C12P 21/00
C12P 21/02
A61P 11/06
C07K 16/24
C12N 5/10

US Classification:

4241391, 5303879, 5303892, 536 2353, 4353201, 435331, 435335, 4352523, 43525233, 435 696, 4241581, 5303873

Abstract:

The present invention relates to target binding members (e.g., antibodies) that bind a specified epitope of human IL-25. The invention also relates to target binding members (e.g., antibodies) that comprise one or more humanized antibody VL domain sequences and bind IL-25. The invention further relates to compositions comprising target binding members (e.g., antibodies) that bind IL-25, methods of producing such target binding members, and uses of such target binding members for the treatment or prevention of diseases and conditions (e.g., asthma, inflammatory bowel disease).

US Patent:

20220411504, Dec 29, 2022

Filed:

May 26, 2021

Appl. No.:

17/330462

Inventors:

- Horsham PA, US
Scott R. Brodeur - New Hope PA, US
Rajkumar Ganesan - Blue Bell PA, US
Jaclyn Hoover - Conshohocken PA, US
Steven A. Jacobs - North Wales PA, US
Colleen M. Kane - Flourtown PA, US
Jinquan Luo - Malvern PA, US
Sanjaya Singh - Blue Bell PA, US
Fang Yi - Collegeville PA, US
Adam Zwolak - Bala Cynwyd PA, US
Triveni K. Bhatt - Perkasie PA, US
Michael Dennis Feldkamp - Blue Bell PA, US
Sherry Lynn La Porte - Horsham PA, US

International Classification:

C07K 16/28
A61P 35/00
C07K 16/30
C07K 16/42

Abstract:

The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.

US Patent:

20230040715, Feb 9, 2023

Filed:

Mar 23, 2022

Appl. No.:

17/701764

Inventors:

- Horsham PA, US
Raymond Brittingham - Blue Bell PA, US
Scott R. Brodeur - New Hope PA, US
Rajkumar Ganesan - Thousand Oaks CA, US
Sherry Lynn La Porte - Horsham PA, US
Jinquan Luo - Malvern PA, US
Fang Yi - Collegeville PA, US
Colleen M. Kane - Flourtown PA, US
Triveni K. Bhatt - Perkasie PA, US

International Classification:

C07K 16/28
C07K 16/46
C12N 15/85

Abstract:

The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3ε, polynucleotides encoding them, vectors, host cells, methods of making and using them.

US Patent:

20200048349, Feb 13, 2020

Filed:

May 21, 2019

Appl. No.:

16/418082

Inventors:

- Horsham PA, US
Bradley HEIDRICH - Gilbertsville PA, US
Chichi HUANG - Malvern PA, US
Colleen KANE - Flourtown PA, US
Ronan MCDAID - Eagleville PA, US

International Classification:

C07K 16/28
A61K 39/395
C07K 16/30
A61P 35/00

Abstract:

The present invention relates to antibodies that specifically bind CD3. The present invention relates to antibodies that specifically bind PSMA. The present invention relates to antibodies that specifically bind CD3 and PSMA. The present invention relates to antibodies that specifically bind IL1RAP. The present invention relates to antibodies that specifically bind CD33. The present invention relates to antibodies that specifically bind CD3 and IL1RAP. The present invention relates to antibodies that specifically bind CD3 and CD33. The present invention relates to antibodies that specifically bind TMEFF2. The present invention relates to antibodies that specifically bind CD3 and TMEFF2. The present invention relates to fragments of the antibodies, polynucleotides encoding the antibodies or fragments thereof, and methods of making and using the same.

US Patent:

20200024360, Jan 23, 2020

Filed:

May 21, 2019

Appl. No.:

16/418328

Inventors:

- Horsham PA, US
Tammy Bush - Perkasie PA, US
Rosa Maria Fernandes Cardoso - Berwyn PA, US
Ellen Chi - Del Mar CA, US
Judith Ann Connor - Vista CA, US
Thai Quang Dinh - Solana Beach CA, US
Derrick Lemon Domingo - Carlsbad CA, US
John Michael Jones - Ambler PA, US
Colleen Kane - Flourtown PA, US
Bethany Kay Mattson - Conoshohocken PA, US
Theresa Marie McDevitt - Warminster PA, US
Jill Marie Mooney - San Diego CA, US
Richard Stephen Tawadros - Norristown PA, US
Hong Mimi Zhou - San Diego CA, US

International Classification:

C07K 16/30
C07K 16/28

Abstract:

The present invention relates to antibodies specifically binding PSMA or PSMA and CD3, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

US Patent:

20190359711, Nov 28, 2019

Filed:

May 21, 2019

Appl. No.:

16/417889

Inventors:

- Horsham PA, US
Robin Ernst - Kintnersville PA, US
Rajkumar Ganesan - Blue Bell PA, US
Colleen Kane - Flourtown PA, US
Michael Russell - West Chester PA, US
Sanjaya Singh - Blue Bell PA, US
Sathyadevi Venkataramani - Blue Bell PA, US
Sheng-Jiun Wu - Broomall PA, US

Assignee:

Janssen Biotech, Inc. - Horsham PA

International Classification:

C07K 16/28
A61P 35/00

Abstract:

The disclosure provided herein relates to monospecific and multispecific anti-TMEFF2 antibodies, and methods of producing and using the described antibodies.