Concetta C Dirusso

US Patent:

8263640, Sep 11, 2012

Filed:

Jun 1, 2010

Appl. No.:

12/791323

Inventors:

Concetta Dirusso - Lincoln NE, US
Paul Black - Lincoln NE, US

Assignee:

NUtech Ventures - Lincoln NE

International Classification:

A01N 43/12
A01N 43/26
A01N 43/36
A01N 43/38
A61K 31/38
A61K 31/385
A61K 31/40

US Classification:

514443, 514411, 514423, 514439

Abstract:

The present disclosure describes inhibitors of fatty acid uptake and methods of using such inhibitors. Specifically, the present disclosure describes inhibitors with specificity for FATP2.

US Patent:

8410118, Apr 2, 2013

Filed:

Aug 10, 2012

Appl. No.:

13/571632

Inventors:

Concetta DiRusso - Lincoln NE, US
Paul Black - Lincoln NE, US

Assignee:

NUtech Ventures - Lincoln NE

International Classification:

A01N 43/90
A01N 43/54
A01N 43/56
A61K 31/519
A61K 31/505
A61K 31/415

US Classification:

5142595, 5142593, 514269, 514406

Abstract:

The present disclosure describes inhibitors of fatty acid uptake and methods of using such inhibitors. Specifically, the present disclosure describes inhibitors with specificity for FATP2.

US Patent:

8431582, Apr 30, 2013

Filed:

Aug 10, 2012

Appl. No.:

13/571667

Inventors:

Concetta DiRusso - Lincoln NE, US
Paul Black - Lincoln NE, US

Assignee:

NUtech Ventures - Lincoln NE

International Classification:

A01N 43/90
A01N 43/54
A01N 43/56
A61K 31/519
A61K 31/505
A61K 31/415

US Classification:

5142595, 5142593, 514269, 514406

Abstract:

The present disclosure describes inhibitors of fatty acid uptake and methods of using such inhibitors. Specifically, the present disclosure describes inhibitors with specificity for FATP2.

US Patent:

20020182197, Dec 5, 2002

Filed:

Mar 14, 2002

Appl. No.:

10/099350

Inventors:

Paul Black - Slingerlands NY, US
Concetta DiRusso - Slingerlands NY, US

International Classification:

A61K038/43

US Classification:

424/094100

Abstract:

Methods for identifying modulators of fatty acid transport and/or uptake, comprising contacting, under conditions favorable for fatty acid uptake, a putative modulator, e.g., an inhibitor with a system comprising genetic material encoding a fatty acid transport mediator (“TTM”), particularly FAA1, FAA2, FAA3, FAA4, FAT1, fadL, fadD, FATP, CD36 and FABP, or orthologs, homologs, isoforms, variants, analogs, derivatives or fragments thereof, and combinations thereof, or fatty acid transport mediator proteins (“TTMps”), e.g., Faa1p, Faa2p, Faa3p, Faa4p, Fat1p, FadL, fatty acyl CoA synthetase, FATP, CD36 and FABP, or orthologs, homologs, isoforms, variants, analogs, derivatives or fragments thereof, and combinations thereof, and determining the effect of the putative modulator. The test system may be a cell such as etc. or an in vitro system.