Craig H Day

US Patent:

6512094, Jan 28, 2003

Filed:

Jun 13, 2000

Appl. No.:

09/593793

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07K 100

US Classification:

530350, 435 911, 435 912, 435 5, 435 6, 42419711, 4241841, 4241851, 536 231, 536 237, 530352, 530380

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6537555, Mar 25, 2003

Filed:

Jun 28, 2001

Appl. No.:

09/894998

Inventors:

Nancy A. Hosken - Seattle WA
Craig H. Day - Seattle WA
Davin C. Dillon - Issaquah WA
Patrick McGowan - Seattle WA
Paul R. Sleath - Seattle WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

A61K 3912

US Classification:

4241991, 4242311, 4241841, 4241861, 4242041, 435 6, 4353201, 435325, 4352351, 536 2372

Abstract:

Compounds and methods for the diagnosis and treatment of HSV infection are provided. The compounds comprise polypeptides that contain at least one antigenic portion of an HSV polypeptide and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits are also provided comprising such polypeptides and/or DNA sequences and a suitable detection reagent for the detection of HSV infection in patients and in biological samples.

US Patent:

6620922, Sep 16, 2003

Filed:

Aug 9, 2000

Appl. No.:

09/636215

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07H 2104

US Classification:

536 231, 536 234, 536 241, 536 2431, 536 2433, 536 235, 435 6, 435 911

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6630305, Oct 7, 2003

Filed:

Oct 10, 2000

Appl. No.:

09/685166

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C12Q 168

US Classification:

435 6, 4353201, 4352523, 435325, 536 231, 536 241

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.

US Patent:

6759515, Jul 6, 2004

Filed:

Oct 2, 2000

Appl. No.:

09/679426

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07K 1400

US Classification:

530350, 514 2, 4241921, 435 6

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.

US Patent:

6800746, Oct 5, 2004

Filed:

Jan 12, 2001

Appl. No.:

09/759143

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C12Q 168

US Classification:

536 231, 435 6, 4352503, 4353201, 435325, 536 241

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.

US Patent:

6818751, Nov 16, 2004

Filed:

Aug 29, 2000

Appl. No.:

09/651236

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07H 2104

US Classification:

536 231, 536 243

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6821519, Nov 23, 2004

Filed:

Sep 6, 2002

Appl. No.:

10/237551

Inventors:

Craig H. Day - Shoreline WA
Nancy A. Hosken - Seattle WA
Joseph M. Parsons - Seattle WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

A61K 39245

US Classification:

4242311, 4242041, 435 911, 530300

Abstract:

Compounds and methods for the diagnosis and treatment of HSV infection are provided. The compounds comprise polypeptides that contain at least one antigenic portion of an HSV polypeptide and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits are also provided comprising such polypeptides and/or DNA sequences and a suitable detection reagent for the detection of HSV infection in patients and in biological samples.