Patrick Schneider - Irvine CA Karen K. Yamamoto - San Clemente CA Cynthia K. French - Irvine CA
Assignee:
Reprogen, Inc. - Costa Mesa CA
International Classification:
C12Q 168
US Classification:
435 6, 435 71, 435 912
Abstract:
Cathepsin S expression is up-regulated in endometriotic tissue. This invention provides methods of diagnosing endometriosis by detecting up-regulation of a cathepsin S gene product, and methods of treating endometriosis by down-regulating expression of cathepsin S in ectopic or eutopic endometriotic tissue.
Cynthia K. French - Irvine CA, US Karen K. Yamamoto - San Clemente CA, US A. Said El Shami - Camarillo CA, US
Assignee:
Diagnostic Products Corporation - Los Angeles CA
International Classification:
G01N033/574 G01N033/53 G01N033/48
US Classification:
435 723, 435 71, 436 64
Abstract:
This invention provides cDNA encoding a prostate-cancer specific marker, Repro-PC-1. 0, Repro-PC-1. 0 polypeptides and methods for use in diagnosis and therapy.
Method For Following The Progress Of Prostate Cancer
Cynthia K. French - Irvine CA, US Karen K. Yamamoto - San Clemente CA, US A. Said El Shami - Old Forge NY, US
Assignee:
Siemens Healthcare Diagnostices, Inc. - Tarrytown NY
International Classification:
G01N 33/574 G01N 33/53 C12Q 1/68
US Classification:
435 723, 435 6, 435 71
Abstract:
This invention provides cDNA encoding a prostate-cancer specific marker, Repro-PC-1. 0, Repro-PC-1. 0 polypeptides and methods for use in diagnosis and therapy.
Cynthia French - Irvine CA, US Karen Yamamoto - San Clemente CA, US
International Classification:
A01K067/00
US Classification:
800/003000, 800/010000
Abstract:
This invention provides methods of identifying hormone-regulated traits in a cell. The methods involve cultivating the cell as a graft in two different hormonal environments and determining whether expression of the trait differs in the two grafts.
Cynthia K. French - Irvine CA Karen K. Yamamoto - Los Angeles CA Phoebe M. Chow - Temple City CA Negemias T. Alido - Chino Hills CA
Assignee:
VivoRx Autoimmune, Inc. - Santa Monica CA
International Classification:
C07K 1400 C07K 500 C07K 200 C12N 1500
US Classification:
530350
Abstract:
An autoantigen identified as HP-8 which is related to systemic lupus erythematosus. The HP-8 antigen is expressed by a gene which was identified by immunoscreening of human placental cDNA GT11 expression library with the monoclonal antibody 3E10. The 3E10 antibody is a low-affinity anti-double-stranded DNA autoantibody derived from the MRL murine models for human systemic lupus erythematosus.
Cynthia K. French - Irvine CA Patrick A. Schneider - Irvine CA Karen K. Yamamoto - San Clemente CA
Assignee:
Diagnostic Products Corporation - Los Angeles CA
International Classification:
C07H 2102 C07H 2104
US Classification:
536 231
Abstract:
This invention provides cDNA encoding a prostate-cancer specific marker, Repro-PC-1. 0, Repro-PC-1. 0 polypeptides and methods for use in diagnosis and therapy.