Dan Cassel Shoemaker

US Patent:

56630620, Sep 2, 1997

Filed:

Nov 30, 1993

Appl. No.:

8/159719

Inventors:

Joseph A. Sorge - Rancho Santa Fe CA
Dan Shoemaker - Del Mar CA

Assignee:

Stratagene - La Jolla CA

International Classification:

C12P 1934
C07H 2104

US Classification:

435 911

Abstract:

A library of oligonucleotides is described comprising a plurality of different oligonucleotides each in separate containers. The oligonucleotides are typically of the same length of from about 5 to 10 nucleotides in length, and each oligonucleotide in the library has the same nucleotide sequence of from 1 to 3 nucleotides in length at the 5' terminus of all the oligonucleotides in the library. In addition methods are described for using the oligonucleotide library for producing oligonucleotides of preselected nucleotide sequence for use in DNA sequencing and primer extension reactions.

US Patent:

55999212, Feb 4, 1997

Filed:

May 8, 1991

Appl. No.:

7/697936

Inventors:

Joseph A. Sorge - Rancho Santa Fe CA
Dan Shoemaker - Del Mar CA
Michael Weiner - San Diego CA

Assignee:

Stratagene - La Jolla CA

International Classification:

C07H 2100
C07H 2104

US Classification:

536 2433

Abstract:

A composition comprising a family of oligonucleotides all of the same length, said family defined by a nucleotide sequence formula containing six to eight nucleotide positions, one to three of said positions of the formula identifying positions of nucleotide variation among the family members, the remaining nucleotide positions each identifying a nucleotide that is the same in all members of the family.