Daniel T Simmons

US Patent:

7179627, Feb 20, 2007

Filed:

Sep 28, 2002

Appl. No.:

10/260937

Inventors:

Daniel Simmons - Provo UT, US
N. Vishvanath Chandrasekharan - Provo UT, US

Assignee:

Brigham Young University - Provo UT

International Classification:

C12N 9/02
C12N 1/20
C12N 15/00
C12Q 1/26
C12P 21/04
A01N 25/00
C07H 21/04
C12Q 1/00
C12Q 1/68

US Classification:

435189, 4352523, 4353201, 435440, 435 4, 435 6, 435 18, 435325, 435 691, 435 711, 536 232, 536 235, 514789

Abstract:

The invention relates to the isolation of novel cyclooxygenase type 1 (COX-1) variant enzymes. More specifically, the invention relates to the identification of cyclooxygenase transcripts harboring inton 1, or fragment thereof, of cyclooxygenase 1. The invention further relates to the diagnosis of aberrant cyclooxygenase type 1 variant gene or gene product; the identification, production, and use of compounds which modulate cyclooxygenase type 1 variant gene expression or the activity of the cyclooxygenase type 1 variant gene product including but not limited to nucleic acid encoding cyclooxygenase type 1 variants and homologues, analogues, and deletions thereof, as well as antisense, ribozyme, triple helix, antibody, and polypeptide molecules as well as small inorganic molecules; and pharmaceutical formulations and routes of administration for such compounds.

US Patent:

7281252, Oct 9, 2007

Filed:

Mar 12, 2003

Appl. No.:

10/387293

Inventors:

Joshua Lindquist - Bellevue WA, US
Daniel Galen Simmons - Sammamish WA, US
Li Wang - Kirkland WA, US
Eric Barber Vigesaa - Seattle WA, US
Gloria Monroe Godfrey - Kirkland WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 13/00

US Classification:

719332, 719330, 719331, 719315, 718104

Abstract:

A method, system, and apparatus for implementing object interfaces at runtime are provided. According to the method, a request is received for a resource that includes a client side object that supports an object interface. In response to the request, program code is generated that implements the interface. Once the program code implementing the object interface has been generated, the requested resource and the program code implementing the object interface are returned in response to the request for the resource. An intermediary object for mediating communication between objects is also generated and returned in response to the request. If the object interface implements an interface for consuming data, the object interface registers itself with the intermediary object as an event consumer. If the object interface implements a provider interface, the object interface calls the intermediary object in response to the occurrence of a specified type of event.

US Patent:

7480921, Jan 20, 2009

Filed:

Sep 30, 2003

Appl. No.:

10/675173

Inventors:

Eric B. Vigesaa - Seattle WA, US
Joshua Lindquist - Bellevue WA, US
Daniel Simmons - Sammamish WA, US
Li Wang - Kirkland WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 13/00

US Classification:

719330, 718104, 709201, 709217, 709218, 709219

Abstract:

A method, system, and apparatus for customizing web part objects. A web part object that is capable of providing a presentation is accessed. Once the web part object is accessed, a specification file associated with the web part object is also accessed. The specification file contains additional code, such as HTML, JAVA Script, or other code. The additional code is applied to a web part to modify the presentation of the web part. Thus, the presentation of the web part is modified in accordance with the specification file to provide a modified presentation.

US Patent:

7526501, Apr 28, 2009

Filed:

Oct 18, 2006

Appl. No.:

11/550574

Inventors:

Benjamin Albahari - Seattle WA, US
Daniel G. Simmons - Sammamish WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 17/30

US Classification:

707102

Abstract:

The claimed subject matter provides a system and/or a method that facilitates handling a change associated with a database. An interface that can receive data associated with a change to data via an object graph. A state transition logic component that can maintain the change related to the object graph utilizing a context and a respective set of rules, the context employs metadata to view the object graph with an abstraction of at least one of an entity and a relationship.

US Patent:

7601816, Oct 13, 2009

Filed:

Nov 17, 2006

Appl. No.:

11/601208

Inventors:

Daniel Simmons - Provo UT, US
N. Vishvanath Chandrasekharan - Provo UT, US

Assignee:

Brigham Young University - Provo UT

International Classification:

C07K 16/00
C07K 16/40

US Classification:

5303879, 5303871, 5303881, 53038826, 5303891

Abstract:

The invention relates to the isolation of novel cyclooxygenase type 1 (COX-1) variant enzymes. More specifically, the invention relates to the identification of cyclooxygenase transcripts harboring inton 1, or fragment thereof, of cyclooxygenase 1. The invention further relates to the diagnosis of aberrant cyclooxygenase type 1 variant gene or gene product; the identification, production, and use of compounds which modulate cyclooxygenase type 1 variant gene expression or the activity of the cyclooxygenase type 1 variant gene product including but not limited to nucleic acid encoding cyclooxygenase type 1 variants and homologues, analogues, and deletions thereof, as well as antisense, ribozyme, triple helix, antibody, and polypeptide molecules as well as small inorganic molecules; and pharmaceutical formulations and routes of administration for such compounds.

US Patent:

8185590, May 22, 2012

Filed:

Dec 2, 2004

Appl. No.:

11/004315

Inventors:

Daniel Simmons - Sammamish WA, US
Josh Lindquist - Bellevue WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 15/16

US Classification:

709206, 709204, 709207

Abstract:

A facility for replicating offline scheduling transactions directed to a server is provided. The facility is implemented as a client-side application that integrates with and utilizes components of a store-and-forward application, which is operable to execute on a client to guarantee that transactions submitted on the client are replicated and carried out on a service hosted on a remote server even in light of intermittent connectivity between the client, the server, and networks. Records describing transactions intended remote service are written to an outbox of the store-and-forward application on the client. When online, the store-and-forward application first invokes the facility, which processes the items in the outbox by iteratively retrieving the items from the outbox and, for each item, determining whether the item is a transaction intended for the scheduling application. If the item is intended for the scheduling application, the facility sends the item to the scheduling application. Otherwise, if the item is not intended for the scheduling application, the facility returns the item to the outbox for processing by other components of the store-and-forward application.

US Patent:

20090327225, Dec 31, 2009

Filed:

Jun 26, 2008

Appl. No.:

12/146862

Inventors:

Sarah M. Parra - Bothell WA, US
Ravinder R. Vuppula - Redmond WA, US
Jeffrey M. Derstadt - Seattle WA, US
Brian Dawson - Redmond WA, US
Michael J. Pizzo - Bellevue WA, US
Patrick T. Magee - Sammamish WA, US
Nadejda V. Poliakova - Redmond WA, US
Daniel G. Simmons - Sammamish WA, US

Assignee:

MICROSOFT CORPORATION - Redmond WA

International Classification:

G06F 17/30
G06F 7/06

US Classification:

707 3, 707103 Y, 707E17014, 707E17048, 707E17055

Abstract:

Systems and methods that enable relationship information to be carried along with the entity when serializing/deserializing entities among application tiers. A tracking component tracks information on relationships associated with an entity, and further enables users to perform subsequent change processing on the entity's relationship information. Accordingly, relationship information can be carried along with the entity such that database operation can be performed without requirement of additional information from the database (e.g., foreign key information that is part of associated graphs).

US Patent:

20120254282, Oct 4, 2012

Filed:

May 22, 2012

Appl. No.:

13/477993

Inventors:

Daniel Simmons - Sammamish WA, US
Josh Lindquist - Bellevue WA, US

Assignee:

Microsoft Corporation - Redmond WA

International Classification:

G06F 15/16

US Classification:

709201

Abstract:

A facility for replicating offline scheduling transactions directed to a server is provided. The facility is implemented as a client-side application that integrates with and utilizes components of a store-and-forward application, which is operable to execute on a client to guarantee that transactions submitted on the client are replicated and carried out on a service hosted on a remote server even in light of intermittent connectivity between the client, the server, and networks. Records describing transactions intended remote service are written to an outbox of the store-and-forward application on the client. If the item is intended for the scheduling application, the facility is invoked by the store-and-forward application to send the item to the scheduling application. Otherwise, the facility returns the item to the outbox for processing by other components of the store-and-forward application.