Daniel Y Cho

US Patent:

8334335, Dec 18, 2012

Filed:

Nov 11, 2011

Appl. No.:

13/294438

Inventors:

Benjamin David Lux - Providence RI, US
Daniel Youngwhan Cho - Pawtucket RI, US
David Alexander Sonshine - Providence RI, US

Assignee:

NuLabel Technologies, Inc. - Providence RI

International Classification:

C08G 18/42
C08K 5/05

US Classification:

524500, 524388

Abstract:

Fluid activatable adhesive compositions and activating fluid(s) for activating the adhesive composition are described herein. The adhesive compositions contain at least two polymers with different hydrophilicities. The hydrophilic polymer has quick tack when exposed to a hydrophilic solvent, such as water or other aqueous solvent, while the hydrophobic polymer provides strong adhesion to a paper or polymeric substrate. The adhesive composition may contain particulate fillers which enable fast exhaustion of the activation fluid out of the adhesive when applied to a substrate, thereby allowing the hydrophobic polymers of the adhesive composition to achieve strong adhesion of the liner-free label to the paper or polymeric substrate. The particulate fillers may also function as anti-blocking agents when liner-free label media are tightly wound in a roll. The adhesive compositions described herein may be used not only on paper, cardboard, and metal, but also on glass and plastics commonly used in commercial applications.

US Patent:

8334336, Dec 18, 2012

Filed:

Nov 11, 2011

Appl. No.:

13/294545

Inventors:

Benjamin David Lux - Providence RI, US
Daniel Youngwhan Cho - Pawtucket RI, US
Felix Perets Shvartsman - New Haven CT, US

Assignee:

NuLabel Technologies, Inc. - Providence RI

International Classification:

C08G 18/42
C08K 5/05

US Classification:

524500, 524388

Abstract:

Fluid activatable adhesive compositions and activating fluid(s) for activating the adhesive composition are described herein. The adhesive compositions contain at least two polymers with different hydrophilicities. The hydrophilic polymer has quick tack when exposed to a hydrophilic solvent, such as water or other aqueous solvent, while the hydrophobic polymer provides strong adhesion to a paper or polymeric substrate. The adhesive composition may contain particulate fillers which enable fast exhaustion of the activation fluid out of the adhesive when applied to a substrate, thereby allowing the hydrophobic polymers of the adhesive composition to achieve strong adhesion of the liner-free label to the paper or polymeric substrate. The particulate fillers may also function as anti-blocking agents when liner-free label media are tightly wound in a roll. The adhesive compositions described herein may be used not only on paper, cardboard, and metal, but also on glass and plastics commonly used in commercial applications.

US Patent:

8536123, Sep 17, 2013

Filed:

Jan 9, 2009

Appl. No.:

12/746863

Inventors:

Daniel J. Cho - Chesterbrook PA, US

Assignee:

Health Onvector Inc. - Pennsauken NJ

International Classification:

A61K 38/18
A61P 7/06
C07K 14/505
G01N 11/00

US Classification:

514 77, 73 5401

Abstract:

A method that includes a measurement of hemoglobin or hematocrit with a measurement of hemodynamic parameters to monitor and/or control a modality of treatment of a patient suffering from anemia.

US Patent:

20100249620, Sep 30, 2010

Filed:

Jul 11, 2008

Appl. No.:

12/668270

Inventors:

Daniel J. Cho - Chesterbrook PA, US

International Classification:

A61B 5/026
G06F 19/00

US Classification:

600504, 702 19

Abstract:

A method for determination of the risk of atherothrombosis that includes determining blood shear stress based on blood viscosity and comparing the blood shear stress to a critical threshold blood shear stress indicative of the propensity of plaque to rupture.

US Patent:

20110275936, Nov 10, 2011

Filed:

May 7, 2010

Appl. No.:

12/775983

Inventors:

Daniel J. Cho - Wayne PA, US
Seul Ki Jeong - Gwangju, KR

International Classification:

A61B 8/00

US Classification:

600438

Abstract:

A method for computing patient specific blood viscosity and patient specific shear stress on a location of interest in the interior of a blood vessel that includes calculating shear rate of blood in the vessel, using imaging techniques and calculating the shear rate related blood viscosity.

US Patent:

20120009267, Jan 12, 2012

Filed:

Jul 8, 2011

Appl. No.:

13/179205

Inventors:

Daniel Cho - Providence RI, US
Joshua Reineke - Providence RI, US
Edith Mathiowitz - Brookline MA, US
Bryan Laulicht - Cambridge MA, US

International Classification:

A61K 9/50
A61K 38/02
A61K 48/00
B29B 9/12
A61K 47/34
A61K 47/32
A61K 47/36
A61K 38/22
A61K 31/713

US Classification:

424497, 514 97, 514 11, 514 44 R, 514 44 A, 5147723, 5147724, 5147726, 514777, 5147727, 264 7

Abstract:

Nanoparticles, compositions, and methods for the improved uptake of active agents are disclosed herein. The compositions contain a monodisperse population of nanoparticles, preferably including an active agent, where the nanoparticles are formed from a polymeric material possessing specified bioadhesion characteristics. Following enteral administration, preferably oral administration, the nanoparticles exhibit total intestinal uptakes of greater than 20%, preferably greater than 45%, more preferably greater than 65%. When compared to uptake of the same composition in the absence of the bioadhesive polymeric material, the nanoparticles have significantly increased uptake with intestinal uptake of the increased by more than 100%, preferably even greater than 500%. Further disclosed herein is a method of producing multi-walled nanoparticles, as well as methods of using thereof. Multi-walled particles prepared using the method disclosed herein are useful for controlling the release of active agents.

US Patent:

20130034726, Feb 7, 2013

Filed:

Feb 6, 2012

Appl. No.:

13/366785

Inventors:

Benjamin David Lux - Providence RI, US
Daniel Youngwhan Cho - Pawtucket RI, US
David Alexander Sonshine - Providence RI, US

International Classification:

C09J 133/08
C09J 179/04
C09J 139/06
G09F 3/10
C09J 7/02

US Classification:

428346, 524503, 524523, 524548, 524612

Abstract:

Fluid activatable adhesive compositions and activating fluid(s) for activating the adhesive composition are described herein. The adhesive compositions contain at least two polymers with different hydrophilicities. The hydrophilic polymer has quick tack when exposed to a hydrophilic solvent, such as water or other aqueous solvent, while the hydrophobic polymer provides strong adhesion to a paper or polymeric substrate. The adhesive composition may contain particulate fillers which enable fast exhaustion of the activation fluid out of the adhesive when applied to a substrate, thereby allowing the hydrophobic polymers of the adhesive composition to achieve strong adhesion of the liner-free label to the paper or polymeric substrate. The particulate fillers may also function as anti-blocking agents when liner-free label media are tightly wound in a roll. The adhesive compositions described herein may be used not only on paper, cardboard, and metal, but also on glass and plastics commonly used in commercial applications.

US Patent:

20130035425, Feb 7, 2013

Filed:

Feb 6, 2012

Appl. No.:

13/366779

Inventors:

Benjamin David Lux - Providence RI, US
Daniel Youngwhan Cho - Pawtucket RI, US
Felix Perets Shvartsman - New Haven CT, US

International Classification:

C09J 147/00
C08K 5/1545
C08K 5/17
C08K 5/06
C08K 3/20
C09J 139/06
C08K 5/315
C08K 5/05
C08K 5/053
C08K 5/09
C08K 5/01
C09J 133/08
C09J 139/04
C08K 5/07

US Classification:

524 17, 524516, 524 27, 524377, 524365, 524205, 524379, 524385, 524383, 524388, 524315

Abstract:

Fluid activatable adhesive compositions and activating fluid(s) for activating the adhesive composition are described herein. The adhesive compositions contain at least two polymers with different hydrophilicities. The hydrophilic polymer has quick tack when exposed to a hydrophilic solvent, such as water or other aqueous solvent, while the hydrophobic polymer provides strong adhesion to a paper or polymeric substrate. The adhesive composition may contain particulate fillers which enable fast exhaustion of the activation fluid out of the adhesive when applied to a substrate, thereby allowing the hydrophobic polymers of the adhesive composition to achieve strong adhesion of the liner-free label to the paper or polymeric substrate. The particulate fillers may also function as anti-blocking agents when liner-free label media are tightly wound in a roll. The adhesive compositions described herein may be used not only on paper, cardboard, and metal, but also on glass and plastics commonly used in commercial applications.