Daniel F Dirocco from Fort Wayne, IN, age 36

view source

view source

Location:

United States

view source

Location:

United States

Process For Making Chloro-Substituted Nucleoside Phosphoramidate Compounds
view source
US Patent:

20170226146, Aug 10, 2017
Filed:

Feb 8, 2017
Appl. No.:

15/427674
Inventors:

John Y.L. Chung - Edison NJ, US
Amude Kassim - Rahway NJ, US
John Limanto - Jersey City NJ, US
Michael Shevlin - Middlesex NJ, US
Peter E. Maligres - Fanwood NJ, US
Daniel A. DiRocco - Lebanon NJ, US
James F. Dropinski - Freehold NJ, US
Rose Mathew - Ringoes NJ, US
Yi Ning Ji Chen - Rahway NJ, US
Edward C. Sherer - Hillsborough NJ, US
Mikhail Reibarkh - Cranford NJ, US
Artis Klapars - Edison NJ, US
Alan Hyde - Rahway NJ, US
Susan L. Zultanski - Brooklyn NY, US
Aaron Moment - New York NY, US
Bryon Simmons - Hamilton NJ, US
Tyler A. Davis - Westfield NJ, US
Timothy James Wright - Clark NJ, US
Ralph Calabria - East Brunswick NJ, US
Louis Charles Campeau - Morris Plains NJ, US
International Classification:

C07H 19/10
C07H 19/24
C07D 487/04
C07H 19/06
Abstract:

The present invention is directed to a process for making Chloro-Substituted Nucleoside Phosphoramidate Compounds of formula (I):which are useful for the treatment and prophylaxis of HCV infection. The present invention is also directed to compounds that are useful as synthetic intermediates for making the compounds of formula (I).