Daniel C Haas

US Patent:

7090764, Aug 15, 2006

Filed:

Jan 15, 2003

Appl. No.:

10/342794

Inventors:

Sridhar G. Iyengar - Somerville MA, US
Daniel Haas - Cambridge MA, US
Craig Bolon - Brookline MA, US

Assignee:

Agamatrix, Inc. - Salem NH

International Classification:

G01N 27/26
G01N 27/416
G01N 31/00
C12Q 1/00

US Classification:

205775, 2057775, 702 23

Abstract:

Systems and methods are provided herein for improving the selectivity and productivity of sensors via digital signal processing techniques. According to one illustrative embodiment, in an electrochemical method for monitoring of a select analyte in a mixed sample with an interfering analyte, an improvement is provided that includes applying a large amplitude potential stimulus waveform to the sample to generate a nonlinear current signal; and resolving a signal contribution from the select analyte in the generated signal by a vector projection method with an analyte vector comprising a plurality of real and imaginary parts of one or more Fourier coefficients at one or more frequencies of a reference current signal for the select analyte.

US Patent:

8303787, Nov 6, 2012

Filed:

Oct 21, 2010

Appl. No.:

12/909087

Inventors:

Sridhar G. Iyengar - Salem NH, US
Daniel Haas - Pasadena CA, US
Craig Bolon - Brookline MA, US
Ian Harding - Wells, GB

Assignee:

Agamatrix, Inc. - Salem NH

International Classification:

G01N 27/327

US Classification:

20440314, 204400

Abstract:

Systems and methods are provided herein for improving the selectivity and productivity of sensors via digital signal processing techniques. According to one illustrative embodiment, in an electrochemical method for monitoring of a select analyte in a mixed sample with an interfering analyte, an improvement is provided that includes applying a large amplitude potential stimulus waveform to the sample to generate a nonlinear current signal; and resolving a signal contribution from the select analyte in the generated signal by a vector projection method with an analyte vector comprising a plurality of real and imaginary parts of one or more Fourier coefficients at one or more frequencies of a reference current signal for the select analyte.

US Patent:

20100219083, Sep 2, 2010

Filed:

Jul 17, 2006

Appl. No.:

11/458025

Inventors:

Sridhar G. Iyengar - Salem NH, US
Daniel Haas - Pasadena CA, US
Craig Bolon - Brookline MA, US

Assignee:

AGAMATRIX, INC. - Salem NH

International Classification:

G01N 27/26
G01N 33/50

US Classification:

205775, 204400, 20440314

Abstract:

Systems and methods are provided herein for improving the selectivity and productivity of sensors via digital signal processing techniques. According to one illustrative embodiment, in an electrochemical method for monitoring of a select analyte in a mixed sample with an interfering analyte, an improvement is provided that includes applying a large amplitude potential stimulus waveform to the sample to generate a nonlinear current signal; and resolving a signal contribution from the select analyte in the generated signal by a vector projection method with an analyte vector comprising a plurality of real and imaginary parts of one or more Fourier coefficients at one or more frequencies of a reference current signal for the select analyte.