Daniel L Keefe

US Patent:

20080009542, Jan 10, 2008

Filed:

Jul 5, 2007

Appl. No.:

11/773892

Inventors:

Elisabeth Brot - Albany NY, US
Daniel Keefe - Troy NY, US
Brian Haney - Rensselaer NY, US
Nigel Metcalfe - Rensselaer NY, US
Grant Palmer - Clifton Park NY, US
Paul Isbester - Castleton NY, US

Assignee:

CeNeRx BioPharma, Inc. - Cary NC

International Classification:

A61K 31/39
A61P 25/00
C07D 497/00

US Classification:

514434000, 549016000

Abstract:

Provided herein is a new form of 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathin 10,10-dioxide, which demonstrates higher stability relative to other forms of 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin-10,10-dioxide. In particular, this new form affords less dosage critical administration of 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathin 10,10-dioxide relative to other forms. The new solid form of 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin-10,10-dioxide has been determined and is provided herein. This new solid form of 3-fluoro-7-(2,2,2-trifluoroethoxy)phenoxathiin-10,10-dioxide can be characterized by any of a number of its properties, including, but not limited to, melting point, differential scanning calorimetry, infrared spectroscopic spectrum or portions thereof, solubility, methods and conditions under which this form is prepared, and/or precipitated from solution, and, when in crystalline form, the crystalline form can be characterized according to the diffraction pattern or portions thereof

Address:

208 Adams St, Delmar, NY 12054

Phone:

(518)4622594

VIN:

KNDMG4C79B6410261

Make:

KIA

Model:

SEDONA

Year:

2011