Daniel T Shea

US Patent:

20180071690, Mar 15, 2018

Filed:

Mar 16, 2016

Appl. No.:

15/558191

Inventors:

- Cambridge MA, US
Donald E. Ingber - Boston MA, US
Miles Ingram - Cambridge MA, US
Daniel Levner - Brookline MA, US
Richard Novak - Jamaica Plain MA, US
Jefferson Puerta - Malden MA, US
Daniel E. Shea - Mendon MA, US
Josiah Sliz - Boston MA, US
Norman Wen - Newton MA, US

International Classification:

B01D 67/00
B01D 71/70
B29C 41/38
B29C 33/42
B29C 33/68
B29C 39/00
B29C 39/26
B29C 41/12
C12M 1/12

Abstract:

A method for micro-molding a polymeric membrane and including pouring a predetermined volume of curable polymer unto a micro-fabricated mold having a post array with pillars, and overlaying the polymer with a support substrate. A spacer, such as a rubber spacer, is placed in contact with the support substrate and a force is applied to an exposed side of the spacer to compress the support substrate and the polymer together. While applying the force, the polymer is cured on the mold for a predetermined time period and at a predetermined temperature to form a polymeric membrane having a pore array with a plurality of pores corresponding to the plurality of pillars of the post array. The polymeric membrane is removed from the support substrate.