Daniel R. Storm - Brier WA, US Beth Hacker - Seattle WA, US James E. Tomlinson - Burlingame CA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA University of Washington - Seattle WA
International Classification:
G01N 33/53 C12N 9/88
US Classification:
435 71, 435232
Abstract:
The invention relates to novel human adenylyl cyclase nucleic acid and amino acid sequences. Also provided are vectors, host cells, recombinant methods for making and using the novel molecules and methods for identifying compounds which bind to the adenylyl cyclase proteins.
Method For Treating Persistent Pain And Identifying Compounds To Treat Persistent Pain
Feng Wei - Ellicott City MD, US Daniel Storm - Seattle WA, US Louis Muglia - St. Louis MO, US Min Zhuo - St. Louis MO, US
International Classification:
A61K039/395
US Classification:
424/146100
Abstract:
Disclosed is method of down-regulating an activity associated with AC1, AC8 or both in a subject comprising administering to the subject an antagonist to AC1, AC8 or both in an amount sufficient to affect the antagonism.
Cloning And Characterization Of A Human Adenylyl Cyclase