David Todd Andrews

US Patent:

6713481, Mar 30, 2004

Filed:

Oct 5, 1998

Appl. No.:

09/166445

Inventors:

David R. Andrews - Maplewood NJ 07040
William Leong - Westfield NJ 07090
Anantha Sudhakar - East Brunswick NJ 08816

International Classification:

A61K 31496

US Classification:

51425407, 544366

Abstract:

The crystalline polymorph Form I of (-)-4-[4-[4-[4-[[(2R-cis)-5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methoxy]phenyl]-1-piperazinyl]phenyl-2,4-dihydro-2-[(S)-1-ethyl-2(S)-hydroxylpropyl]-3H-1,2,4-triazol-3-one represented by the formula I pharmaceutical compositions containing such a polymorph and methods of using such a polymorph to treat fungal infections in mammals are disclosed.

US Patent:

6958337, Oct 25, 2005

Filed:

Feb 25, 2004

Appl. No.:

10/786886

Inventors:

David R. Andrews - Maplewood NJ, US
William Leong - Westfield NJ, US
Anantha Sudhakar - East Brunswisk NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K031/496
C07D405/14

US Classification:

51425407, 544366

Abstract:

The crystalline polymorph Form I of (−)-4-[4-[4-[4-[[(2R-cis)-5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methoxy]phenyl]-1-piperazinyl]phenyl-2,4-dihydro-2-[(S)-1-ethyl-2(S)-hydroxylpropyl]-3H-1,2,4-triazol-3-one represented by the formula I pharmaceutical compositions containing such a polymorph and methods of using such a polymorph to treat fungal infections in mammals are disclosed.

US Patent:

7129357, Oct 31, 2006

Filed:

Sep 13, 2004

Appl. No.:

10/939740

Inventors:

David R. Andrews - Maplewood NJ, US
Suhan Tang - Plainsboro NJ, US
Wenxue Wu - Princeton Junction NJ, US
Sami Y. Kalliney - Chatham NJ, US
Anantha Sudhakar - Freemont CA, US
Christopher Nielsen - Westfield NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D 215/20
C07D 215/38

US Classification:

546169, 546170, 560 23

Abstract:

In one embodiment, the present application discloses a process for making the compound of the formula:.

US Patent:

20130159030, Jun 20, 2013

Filed:

Dec 19, 2012

Appl. No.:

13/720477

Inventors:

David Andrews - Little Silver NJ, US
Richard Miglin - Kinnelon NJ, US
Robert O'Connor - Harwinton CT, US

Assignee:

The Shubert Organization, Inc. - New York NY

International Classification:

G06Q 10/02

US Classification:

705 5

Abstract:

Ticketing systems and methods, as well as related computer product programs, provide efficient and user-friendly seat selection by incorporating realistic seating charts. An advantageous ticketing system may include data related to a physical layout of a venue. The ticketing system may generate a three-dimensional model of the venue, from which one or more seating charts may in turn be generated. A user may search the ticketing system for seats based on customized user search parameters, which may include searching across multiple performances. In response to the user search, the ticketing system may provide an interactive three-dimensional seating chart depicting a relatively accurate seat layout based on the venue data. The user may manipulate the seating chart to view the venue from various perspectives, and the user may select seats from the seating chart. Other embodiments of the ticketing system are also disclosed herein.

US Patent:

45593400, Dec 17, 1985

Filed:

Nov 25, 1983

Appl. No.:

6/555311

Inventors:

Bernard R. Neustadt - West Orange NJ
David R. Andrews - Bloomfield NJ
Paul E. McNamara - Westfield NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D41712
A61K 3154

US Classification:

514222

Abstract:

There are disclosed benzothiadiazinyl and quinazolinyl substituted carboxylalkyl dipeptides, wherein the benzothiodiazinyl or quinazolinyl portions are joined to the dipeptide portions by an aminocarbonyl group. Compounds of this invention are useful as antihypertensive agents, in the treatment of congestive heart failure and in the treatment of glaucoma. In addition, compounds of this invention have diuretic activity.

US Patent:

50156411, May 14, 1991

Filed:

May 9, 1989

Appl. No.:

7/349369

Inventors:

David R. Andrews - South Orange NJ
Federico C. A. Gaeta - Rockaway Township, Morris County NJ
Robert W. Watkins - Great Meadows NJ

International Classification:

A61K 3154

US Classification:

5142235

Abstract:

Pharmaceutical compositions and a method for reducing intraocular pressure by topically applying a carboxyalkyl dipeptide are disclosed.

US Patent:

56167776, Apr 1, 1997

Filed:

Apr 19, 1995

Appl. No.:

8/425129

Inventors:

David R. Andrews - Maplewood NJ
Anantha Sudhakar - East Brunswick NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07C26904
C07C24312

US Classification:

560 29

Abstract:

Disclosed are chiral hydrazine derivatives of the formula (Ia), (Ib), (Ic) and (Id) ##STR1## wherein: R. sup. 1 and R. sup. 2 are independently C. sub. 1 -C. sub. 10 alkyl; R. sup. 3 is H or R. sup. 4 wherein R. sup. 4 is a hydroxy protecting group; and Z is H, --CHO, --C(O)OC(CH. sub. 3). sub. 3 or --C(O)OCH. sub. 2 C. sub. 6 H. sub. 5. Also described is a process for preparing chiral hydrazines of the formula (Ia), (Ib), (Ic) and (Id).

US Patent:

46160124, Oct 7, 1986

Filed:

Nov 12, 1985

Appl. No.:

6/797104

Inventors:

Bernard R. Neustadt - West Orange NJ
David R. Andrews - Bloomfield NJ
Paul E. McNamara - Scotch Plains NJ
Robert W. Watkins - Great Meadows NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 3154

US Classification:

514222

Abstract:

Methods and pharmaceutical compositions are disclosed for reducing intraocular pressure. The methods and compositions employ an active ingredient which comprises certain benzothiadiazinyl and quinazolinyl substituted carboxyalkyl dipeptides wherein the benzothiadiazinyl or quinazolinyl portions are joined to the dipeptide portions by an aminocarbonyl group.