David J Chan

US Patent:

50527029, Oct 1, 1991

Filed:

Jun 5, 1990

Appl. No.:

7/533447

Inventors:

David M. Chan - San Gabriel CA

International Classification:

A63O 1702

US Classification:

280 1128

Abstract:

A toy skateboard is provided with steerable truck assemblies having a minimum of parts. Two longitudinally spaced pivots on the underside of the platform hold the trucks on the platform. A leaf spring with three prongs is placed between each truck and the platform. One or more of the prongs are bent away from the plane of the body of the spring with the two outer prongs always located in the same direction. The diameter of the pivots is less than the diameter of the holes through the trucks allowing the trucks to be tilted in any direction about the pivots. Limit walls molded on the undersurface of the platform limit the rotation of the trucks about the pivots. When the platform is tilted, the springs push the trucks out of the straight forward position into the direction of the tilt thereby mimicking the action of a full sized skateboard.

US Patent:

49307940, Jun 5, 1990

Filed:

Aug 29, 1988

Appl. No.:

7/237709

Inventors:

David M. Chan - San Gabriel CA

International Classification:

A63L 1702

US Classification:

280 1128

Abstract:

A toy skateboard is provided with steerable truck assemblies having a minimum of parts. Two longitudinally spaced pivots on the underside of the platform hold the trucks on the platform. A leaf spring with three prongs is placed between each truck and the platform. One or more of the prongs are bent away from the plane of the body of the spring with the two outer prongs always located in the same direction. The diameter of the pivots is less than the diameter of the holes through the trucks allowing the trucks to be tilted in any direction about the pivots. Limit walls molded on the undersurface of the platform limit the rotation of the trucks about the pivots. When the platform is tilted, the springs push the trucks out of the straight forward position into the direction of the tilt thereby mimicking the action of a full sized skateboard.

US Patent:

D3114511, Oct 23, 1990

Filed:

Aug 8, 1988

Appl. No.:

7/229487

Inventors:

David M. Chan - San Gabriel CA

US Classification:

D 3 62

US Patent:

20200053991, Feb 20, 2020

Filed:

Oct 30, 2017

Appl. No.:

16/346003

Inventors:

- Chester PA, US
- Philadelphia PA, US
John Svaren - Madison WI, US
David C. Chan - Pasadena CA, US
Steven S. Scherer - Media PA, US
Taleen Hanania - Valhalla NY, US

International Classification:

A01K 67/027
C12N 9/14

Abstract:

The present invention relates to the engineering an animal model, preferably mammalian models, more preferably a rat model representing Charcot-Marie-Tooth disease 2A (CMT2A) harboring the p.Arg364Trp or p.His361Tyr Mfn2 mutation, whose human counterpart results in a severe, early-onset axonal neuropathy. A model having the p.Arg364Trp Mfn2 mutation is based on a mutation made using zinc finger endonuclease technology in fertilized rat eggs. Cohorts of mutants and wild type littermates were characterized behaviorally and shown to develop multiple motor deficits that worsened over time. Separate cohorts of mutant and wild type rats sacrificed at 7, 40, and 48 weeks and analyzed by light microscopy showed a reduced density of myelinated axons and active axonal degeneration in distal but not proximal nerves, as well as axonal degeneration in the fasciculus gracilis of the cervical spinal cord at 40 and 48 weeks. These findings were not present in the 7-week-old cohort of Mfn2 mutants, or in wild type rats at 7 or 40 weeks. A model having the p.His361Tyr Mfn2 mutation is based on a mutation made using CRISPR/Cas9 gene editing technology. This mutation showed abnormalities in gait dynamics at 8 weeks and a lengthening of the gait cycle at 16 weeks. A genetically authentic animal model for CMT2A developing a progressive axonal neuropathy is a valuable tool for examining the pathogenesis and treatment of CMT2A.

US Patent:

20160283692, Sep 29, 2016

Filed:

Jul 23, 2015

Appl. No.:

14/807144

Inventors:

- Danbury CT, US
David Shoichi Chan - Los Angeles CA, US

International Classification:

G06F 19/00

Abstract:

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for linking a first electronic data set to a second set of data fields in a second electronic data set. Automatically identifying a prescribing physician identifier based on the linked first and second electronic data sets. Determining a relationship between a physician associated with the prescribing physician identifier and at least one of the approved entities based on comparing the prescribing physician identifier and identifiers of the one or more approved entities to a fourth set of data fields from a fourth electronic data set. Automatically generating an electronic notification indicating that a product sold by the merchant is eligible for the discount in response to determining a relationship between a physician and the at least one of the approved entities.