David S Cheng

US Patent:

6785553, Aug 31, 2004

Filed:

Apr 24, 2001

Appl. No.:

09/841110

Inventors:

Donald C. D. Chang - Thousand Oaks CA
Kar W. Yung - Torrance CA
David C. Cheng - Boston MA
Ming U. Chang - Rancho Palos Verdes CA
Frank A. Hagen - Palos Verdes Estates CA

Assignee:

The Directv Group, Inc. - El Segundo CA

International Classification:

H04Q 720

US Classification:

4554565, 4554566, 3423571, 34235714, 342358

Abstract:

A method and system for using two-way ranging navigation to accurately determine the location of a transponder platform above-Earth or a fixed or mobile target on the ground or on water. The two-way ranging navigation measurements are used as calibration references, thereby improving the positioning accuracy of GPS. The system includes GPS and a two-way ranging navigation system for taking position measurements of a target. A correction factor is determined as a function of the measurements and the GPS position is adjusted by the correction factor. The method for calibrating GPS using two-way ranging navigation involves taking a two-way ranging navigation measurement and a GPS measurement of a target, determining a correction factor as a function of the measurements, and correcting the GPS position by taking a second GPS measurement and adjusting it by the correction factor.

US Patent:

20220372456, Nov 24, 2022

Filed:

Jul 10, 2020

Appl. No.:

17/626072

Inventors:

- Cambridge MA, US
David R. Cheng - Boston MA, US
Winston X. Yan - Boston MA, US
Tia Marie Ditommaso - Waltham MA, US

International Classification:

C12N 9/22
C12N 15/11
C12N 15/90
C12N 15/10

Abstract:

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US Patent:

20220315913, Oct 6, 2022

Filed:

Jun 12, 2020

Appl. No.:

17/619165

Inventors:

- Cambridge MA, US
David R. Cheng - Boston MA, US
Winston X. Yan - Boston MA, US

International Classification:

C12N 15/10
C07K 14/195
C12N 9/22

Abstract:

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US Patent:

20220282283, Sep 8, 2022

Filed:

Sep 4, 2020

Appl. No.:

17/634461

Inventors:

- Cambridge MA, US
David R. Cheng - Boston MA, US
Winston X. Yan - Boston MA, US
Tia M. Ditommaso - Waltham MA, US

International Classification:

C12N 15/90
C07K 14/195
C12N 9/22
C12N 15/10
C12N 15/113
C12N 15/86

Abstract:

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US Patent:

20220282308, Sep 8, 2022

Filed:

Sep 9, 2020

Appl. No.:

17/641523

Inventors:

- Cambridge MA, US
David R. CHENG - Boston MA, US
Winston X. YAN - Boston MA, US
Tia M. DITOMMASO - Waltham MA, US

International Classification:

C12Q 1/6823
C12N 1/20
C12N 5/071
C12N 15/11
C12N 9/22
C12N 15/70
C12N 15/85

Abstract:

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US Patent:

20230057102, Feb 23, 2023

Filed:

Aug 17, 2022

Appl. No.:

17/820444

Inventors:

- Cambridge MA, US
David R. Cheng - Boston MA, US
Winston X. Yan - Boston MA, US
Tia M. DiTommaso - Waltham MA, US

International Classification:

C12N 9/22
C12N 15/11
C12N 15/90
C12N 1/20
C12N 5/071
C12N 15/70
C12N 15/85
C12Q 1/6823

Abstract:

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.

US Patent:

20230045187, Feb 9, 2023

Filed:

Dec 3, 2020

Appl. No.:

17/782254

Inventors:

- Cambridge MA, US
Winston X. Yan - Boston MA, US
David R. Cheng - Boston MA, US
Tia M. DiTommaso - Waltham MA, US

International Classification:

C12N 9/22
C12N 15/11
C12N 15/90

Abstract:

The present invention relates to genes coding for nucleases, processes for characterizing the nucleases, cells comprising the nucleases, and methods of using the nucleases.

US Patent:

20230016656, Jan 19, 2023

Filed:

Aug 26, 2020

Appl. No.:

17/638065

Inventors:

- Cambridge MA, US
David R. Cheng - Boston MA, US
Winston X. Yan - Boston MA, US
Tia M. Ditommaso - Waltham MA, US

International Classification:

C12N 9/22
C12N 15/11
C12N 15/90

Abstract:

The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.