David C Clay

US Patent:

20210402075, Dec 30, 2021

Filed:

May 6, 2021

Appl. No.:

17/313424

Inventors:

- Monmouth Junction NJ, US
Vincent J. Capponi - Lawrenceville NJ, US
David R. Clay - West Orange NJ, US

International Classification:

A61M 1/36
A61M 1/34
A61M 1/02
B01J 20/28
B01J 20/32
A01N 1/02
B01J 20/26

Abstract:

The invention concerns methods of removing undesirable molecules from the blood or physiologic fluid; said method comprising contacting said blood or physiologic fluid with a sorbent, said sorbent comprising a plurality of solid forms and comprising a cross-linked polymeric material having a plurality of ligands attached to the surface of said cross-linked polymeric material, comprising (i) zwitterionic moieties, (ii) oligo(ethylene glycol) moieties or (iii) mixtures thereof; said contacting comprising said sorbent sorbing a plurality of said undesirable molecules when said sorbent is administered within a patient's body.

US Patent:

20200246532, Aug 6, 2020

Filed:

Apr 17, 2020

Appl. No.:

16/851305

Inventors:

- Monmouth Junction NJ, US
Vincent J. Capponi - Lawrenceville NJ, US
David R. Clay - West Orange NJ, US

International Classification:

A61M 1/36
A61M 1/34
B01J 20/32
B01J 20/26
A01N 1/02
B01J 20/28
A61M 1/02

Abstract:

The invention concerns methods of removing undesirable molecules from the blood or physiologic fluid; said method comprising contacting said blood or physiologic fluid with a sorbent, said sorbent comprising a plurality of solid forms and comprising a cross-linked polymeric material having a plurality of ligands attached to the surface of said cross-linked polymeric material, comprising (i) zwitterionic moieties, (ii) oligo(ethylene glycol) moieties or (iii) mixtures thereof; said contacting comprising said sorbent sorbing a plurality of said undesirable molecules when said sorbent is administered within a patient's body.

US Patent:

20140294751, Oct 2, 2014

Filed:

Mar 31, 2014

Appl. No.:

14/230108

Inventors:

- Monmouth Junction NJ, US
Vincent J. Capponi - Monmouth Junction NJ, US
David R. Clay - West Orange NJ, US

Assignee:

CytoSorbents Corporation - Monmouth Junction NJ

International Classification:

A61M 1/36
A61K 31/785
A61K 31/765
A61M 1/34

US Classification:

424 7827, 210692, 210263, 424 7818

Abstract:

The invention concerns methods of treating blood, blood product, or physiologic fluid to provide at least one of (i) increasing shelf life of the blood, blood product or physiologic fluid, (ii) maintaining freshness of new blood, blood product or physiologic fluid, and (iii) removing undesirable molecules from the blood, blood product or physiologic fluid; said method comprising contacting said blood, blood product or physiologic fluid with a sorbent, said sorbent being primarily in a plurality of solid forms and comprising a cross-linked polymeric material having a plurality of at least one of (1) zwitterionic moieties and (2) oligo(ethylene glycol) moieties attached to the surface of said cross-linked polymeric material.