David N Haney

US Patent:

6514710, Feb 4, 2003

Filed:

Apr 5, 1999

Appl. No.:

09/285783

Inventors:

Terence R. Jones - San Diego CA
David N. Haney - Mercer Island WA
Janos Varga - Napa CA

Assignee:

Angstrom Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61K 3812

US Classification:

435 72, 514 2, 514 11

Abstract:

Cyclic peptide compounds having 11 amino acids joined by a linking unit L, such that the linear dimension between the C carbon of the first amino acid and the C carbon of eleventh amino acid is between about 4 and 12 ngstrom units; are useful for inhibiting the binding of uPA to the uPAR receptor. Methods for using the cyclic peptide compounds, and compositions containing them, for inhibiting the growth or metastasis of cancerous tumors are also disclosed.

US Patent:

20030166514, Sep 4, 2003

Filed:

Jan 22, 2003

Appl. No.:

10/349543

Inventors:

Terence Jones - San Diego CA, US
David Haney - Mercer Island WA, US
Janos Varga - Napa CA, US

International Classification:

A61K038/12
C07K007/64

US Classification:

514/009000, 530/317000

Abstract:

Cyclic peptide compounds having 11 amino acids joined by a linking unit L, such that the linear dimension between the C carbon of the first amino acid and the C carbon of eleventh amino acid is between about 4 and 12 ngstrom units; are useful for inhibiting the binding of uPA to the uPAR receptor.: Methods for using the cyclic peptide compounds, and compositions containing them, for inhibiting the growth or metastasis of cancerous tumors are also disclosed.

US Patent:

52272427, Jul 13, 1993

Filed:

Jun 6, 1990

Appl. No.:

7/533970

Inventors:

Rebecca S. Walter - Appleton WI
Paulette M. Rosch - Appleton WI
David N. Haney - San Diego CA

Assignee:

Kimberly-Clark Corporation - Neenah WI

International Classification:

B32B 2308

US Classification:

428446

Abstract:

Facial tissues containing a silicone compound exhibit improved softness, and reduced lint while maintaining absorbency. At the same time, the tissues of this invention do not smear glass as is the case with commercially available lotion-treated tissues.

US Patent:

59424923, Aug 24, 1999

Filed:

Nov 12, 1996

Appl. No.:

8/747915

Inventors:

Terence R. Jones - San Diego CA
David N. Haney - Mercer Island WA
Janos Varga - Napa CA

Assignee:

Angstrom Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61K 3812
A61K 3808
A61K 3800

US Classification:

514 15

Abstract:

Cyclic peptide compounds having 11 amino acids joined by a linking unit L, such that the linear dimension between the C. sup. alpha. carbon of the first amino acid and the C. sup. alpha. carbon of eleventh amino acid is between about 4 and 12. ANG. ngstrom units; are useful for inhibiting the binding of uPA to the uPAR receptor. Methods for using the cyclic peptide compounds, and compositions containing them, for inhibiting the growth or metastasis of cancerous tumors are also disclosed.

US Patent:

49505459, Aug 21, 1990

Filed:

Feb 24, 1989

Appl. No.:

7/316048

Inventors:

Rebecca S. Walter - Appleton WI
Paulette M. Rosch - Appleton WI
David N. Haney - San Diego CA

Assignee:

Kimberly-Clark Corporation - Neenah WI

International Classification:

B32B 2700
B32B 904
D04H 100

US Classification:

428446

Abstract:

Facial tissues containing a silicone compound exhibit improved softness, and reduced lint while maintaining absorbency. At the same time, the tissues of this invention do not smear glass as is the case with commercially available lotion-treated tissues.

US Patent:

56860650, Nov 11, 1997

Filed:

Mar 27, 1991

Appl. No.:

7/675749

Inventors:

David N. Haney - San Diego CA

Assignee:

Special Advanced Biomaterials, Inc. - Ogdensburg WI

International Classification:

A61K 742
A61K 744

US Classification:

424 59

Abstract:

Methods and compositions that provide for the long-term adhesion and slow-release of various bioactive agents on the surface of human skin utilize siloxane bridging agents activated for reaction with the skin surface which bind the bioactive agent to the skin surface. Since the topical agent remains bound to the continuously renewing epidermis, safety is enhanced for many bioactive agents. Slight modifications of the siloxane bridging compounds or bioactive agents allows for more or less adhesion to the skin, controlling the degree of release of the agent. Skin treatments according to the invention can provide enhanced repellency to microorganisms, insect bites, sun, water, poison ivy/oak, and other skin irritants, and other effects such as artificial skin coloring and administration of topical drugs, among others.

US Patent:

58919147, Apr 6, 1999

Filed:

Jun 7, 1995

Appl. No.:

8/487027

Inventors:

David N. Haney - San Diego CA

Assignee:

Special Advanced Biomaterials, Inc. - Ogdensburg WI

International Classification:

A61K 31695

US Classification:

514569

Abstract:

Methods and compositions that provide for the long-term adhesion and slow-release of various bioactive agents on the surface of human skin utilize siloxane bridging agents activated for reaction with the skin surface which bind the bioactive agent to the skin surface. Since the topical agent remains bound to the continuously renewing epidermis, safety is enhanced for many bioactive agents. Slight modifications of the siloxane bridging compounds or bioactive agents allows for more or less adhesion to the skin, controlling the degree of release of the agent. Skin treatments according to the invention can provide enhanced repellency to microorganisms, insect bites, sun, water, poison ivy/oak, and other skin irritants, and other effects such as artificial skin coloring and administration of topical drugs, among others.