David T Jaeger

US Patent:

20050266031, Dec 1, 2005

Filed:

May 25, 2004

Appl. No.:

10/852946

Inventors:

Jay Dickerson - Midlothian VA, US
William Mark - Mechanicsville VA, US
Annabelle Trimmer - Manakin-Sabot VA, US
David Jaeger - Chester VA, US
Amanda Alley - Midlothian VA, US

International Classification:

A61K009/00
A61K009/14

US Classification:

424400000, 424488000

Abstract:

An aqueous oral liquid pharmaceutical composition system with reduced propensity for agglomeration and phase separation which is particularly amendable to the suspension of one or more pharmaceutical actives that are substantially insoluble in water. The oral liquid pharmaceutical composition may further comprise pharmaceutical actives that are soluble in water and dissolve in the aqueous medium. In the composition of the invention both suspended and any dissolved active agents are distributed homogeneously.

US Patent:

20060121066, Jun 8, 2006

Filed:

Jan 27, 2005

Appl. No.:

10/485858

Inventors:

David Jaeger - Chester VA, US
Jay Dickerson - Midlothian VA, US
Annabelle Trimmer - Manakin Sabot VA, US

International Classification:

A61K 31/7012
A61K 31/495
A61K 9/00

US Classification:

424400000, 514053000, 514255040

Abstract:

The present invention is directed to a pharmaceutically acceptable taste masking liquid excipient base for administration of a relatively large amount of unpleasant tasting medicines. More particularly, the enhanced sweetness and taste masking effect are produced by the addition of sucralose to the excipient base with maintenance of a pH from about 2 to about 5. The invention is further directed to medicinal compositions comprising such a liquid excipient base and unpleasant tasting medicines. Still further, the invention is directed to a method for taste masking unpleasant tasting medicines through their incorporation into the claimed liquid excipient bases.

US Patent:

20090176884, Jul 9, 2009

Filed:

Mar 12, 2009

Appl. No.:

12/403081

Inventors:

Jay Dickerson - Midlothian VA, US
William Mark - Glen Allen VA, US
Annabelle Trimmer - Manakin-Sabot VA, US
David Jaeger - Chester VA, US
Amanda Roop Alley - Midlothian VA, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/192

US Classification:

514570

Abstract:

An aqueous oral liquid pharmaceutical composition system with reduced propensity for agglomeration and phase separation which is particularly amendable to the suspension of one or more pharmaceutical actives that are substantially insoluble in water. The oral liquid pharmaceutical composition may further comprise pharmaceutical actives that are soluble in water and dissolve in the aqueous medium. In the composition of the invention both suspended and any dissolved active agents are distributed homogeneously.

US Patent:

20110136851, Jun 9, 2011

Filed:

Feb 1, 2011

Appl. No.:

13/018932

Inventors:

David Jaeger - Chester VA, US
Jay Dickerson - Midlothian VA, US
Annabelle Trimmer - Manakin Sabot VA, US

Assignee:

Wyeth LLC - Madison NJ

International Classification:

A61K 31/485
A61K 31/4402
A61K 31/09
A61K 31/137
A61K 31/192
A61K 31/167
A61P 29/00
A61P 11/14
A61P 11/10
A61P 11/02

US Classification:

514289, 514357, 514718, 514653, 514570, 514569, 514629

Abstract:

The present invention is directed to a pharmaceutically acceptable taste masking liquid excipient base for administration of a relatively large amount of unpleasant tasting medicines. More particularly, the enhanced sweetness and taste masking effect are produced by the addition of sucralose to the excipient base with maintenance of a pH from about 2 to about 5. The invention is further directed to medicinal compositions comprising such a liquid excipient base and unpleasant tasting medicines. Still further, the invention is directed to a method for taste masking unpleasant tasting medicines through their incorporation into the claimed liquid excipient bases.

US Patent:

20170065567, Mar 9, 2017

Filed:

Nov 11, 2016

Appl. No.:

15/349101

Inventors:

- New York NY, US
William Mark - Glen Allen VA, US
Annabelle Trimmer - Manakin-Sabot VA, US
David Jaeger - Chester VA, US
Amanda Alley - Midlothian VA, US

Assignee:

Wyeth LLC - New York NY

International Classification:

A61K 31/4402
A61K 31/192
A61K 31/137
A61K 47/18
A61K 47/38
A61K 47/26
A61K 47/10
A61K 47/12
A61K 9/00
A61K 47/36

Abstract:

An aqueous oral liquid pharmaceutical composition system with reduced propensity for agglomeration and phase separation which is particularly amendable to the suspension of one or more pharmaceutical actives that are substantially insoluble in water. The oral liquid pharmaceutical composition may further comprise pharmaceutical actives that are soluble in water and dissolve in the aqueous medium. In the composition of the invention both suspended and any dissolved active agents are distributed homogeneously.

US Patent:

20140142187, May 22, 2014

Filed:

Jan 28, 2014

Appl. No.:

14/165887

Inventors:

- New York NY, US
William Mark - Glen Allen VA, US
Annabelle Trimmer - Manakin-Sabot VA, US
David Jaeger - Chester VA, US
Amanda Alley - Midlothian VA, US

Assignee:

Wyeth LLC - New York NY

International Classification:

A61K 9/10
A61K 47/36
A61K 47/38
A61K 31/192

US Classification:

514570

Abstract:

An aqueous oral liquid pharmaceutical composition system with reduced propensity for agglomeration and phase separation which is particularly amendable to the suspension of one or more pharmaceutical actives that are substantially insoluble in water. The oral liquid pharmaceutical composition may further comprise pharmaceutical actives that are soluble in water and dissolve in the aqueous medium. In the composition of the invention both suspended and any dissolved active agents are distributed homogeneously.