David M Rosenthal

Address:

341 Lands Ml SE, Marietta, GA 30067

Phone:

(770)9520350

VIN:

JTHBL46F995088404

Make:

LEXUS

Model:

LS 460

Year:

2009

US Patent:

6612976, Sep 2, 2003

Filed:

Jun 12, 2001

Appl. No.:

09/879551

Inventors:

David Rosenthal - Marietta GA
Brian Gannon - Walpole MA

Assignee:

Isotech, L.L.C. - Atlanta GA

International Classification:

A61N 500

US Classification:

600 1, 424 165

Abstract:

This invention involves radioactive medical devices for inhibiting an undesirable hyperplastic response in biological tissue, and a method for making the radioactive medical devices. In a first preferred embodiment, a medical device for inhibiting a hyperplastic response in biological tissue generally comprises polymeric hydrocarbon molecules forming the medical device and a salt or an acid of a radioactive isotope occluded within the polymeric hydrocarbon molecules. In a second preferred embodiment, the medical device comprises a thrombogenic sponge having a radioisotope trapped within the structure of the sponge. Also in a preferred embodiment, a method of creating a medical device according to the present invention comprises: providing a first solvent in a container; introducing a salt or an acid of a radioactive isotope into the first solvent; introducing a second solvent into the first solution so as to form a second solution; and introducing the medical device into the second solution, wherein the ionic components of the radioactive isotope migrate into the molecular structure of the medical device. In another aspect, a method of creating a medical device that inhibits a hyperplastic response in biological tissue comprises placing a salt or an acid of a radioactive isotope in a fluid and permitting the salt or acid to disassociate in solution, submersing the sponge in the solution and permitting the radioactive isotopes to become trapped in the structure of the sponge.

US Patent:

6616592, Sep 9, 2003

Filed:

Nov 13, 2000

Appl. No.:

09/711766

Inventors:

David Rosenthal - Marietta GA
Brian Gannon - Walpole MA

Assignee:

Isotech, L.L.C. - Atlanta GA

International Classification:

A61N 500

US Classification:

600 3

Abstract:

This invention involves radioactive medical devices for inhibiting an undesirable hyperplastic response in biological tissue, and a method for making the radioactive medical devices. In a preferred embodiment, a medical device for inhibiting a hyperplastic response in biological tissue generally comprises polymeric hydrocarbon molecules forming the medical device and a salt or an acid of a radioactive isotope occluded within the polymeric hydrocarbon molecules. Also in a preferred embodiment, a method of creating a medical device according to the present invention comprises: providing a first solvent in a container; introducing a salt or an acid of a radioactive isotope into the first solvent; introducing a second solvent into the first solution so as to form a second solution; and introducing the medical device into the second solution, wherein the ionic components of the radioactive isotope migrate into the molecular structure of the medical device.

US Patent:

53757254, Dec 27, 1994

Filed:

Dec 9, 1993

Appl. No.:

8/164209

Inventors:

David Rosenthal - Brooklyn NY

Assignee:

Thomson-Leeds Company, Inc. - New York NY

International Classification:

A47F 700

US Classification:

211 591

Abstract:

A peg hook for dispensing suspended packages or other articles has a resilient tongue near its front end for preventing removal of more than one article at a time. The hook is preferably formed as one piece of plastic material and has spaced fingers for fitting into holes in a pegboard backing panel so that the hook extends horizontally.

US Patent:

60426004, Mar 28, 2000

Filed:

Jan 25, 1999

Appl. No.:

9/236756

Inventors:

David Rosenthal - Marietta GA
Stephen A. Sosnowski - Vista CA

International Classification:

A61B 1704

US Classification:

606224

Abstract:

Generally described, the present invention comprises a medical device for implantation in biological tissue and a method of making the medical device. The medical device comprises an organic compound forming at least a portion of the medical device and a beta radiation emitting element chemically bonded to the organic compound of the medical device. The beta emitter preferably causes the medical device to generate a beta radiation greater than 0. 0002. mu. Ci/cm. The beta radiation emitting element can be tritium preferably incorporated into the organic compound of the medical device by a Wilzbach process. The Wilzbach process involves an entropic exchange of the beta emitting element for elemental hydrogen in a vacuum sealed reaction chamber. On the other hand, the beta radiation emitting element may comprise Carbon 12, or other similar beta emitter, which is incorporated directly into the backbone of the organic compound prior to manufacturing the medical device from the organic compound. In another aspect of the present invention, rather than placing the medical device itself in a reaction chamber for incorporation of a beta emitting element, a mass of organic material may be placed in a reaction chamber.

US Patent:

57073899, Jan 13, 1998

Filed:

Jun 7, 1995

Appl. No.:

8/486038

Inventors:

Frank Louw - Carlsbad CA
Stephen A. Sosnowski - Oceanside CA
David Rosenthal - Marietta GA

Assignee:

Baxter International Inc. - Deerfield IL

International Classification:

A61B 2900

US Classification:

606200

Abstract:

The device for blocking (e. g. , embolizing) the side branches of an anatomical passageway under endoscopic guidance. The device comprises an elongate catheter body having a side branch blocking apparatus, such as an embolization catheter, disposed therein and further incorporating an endoscope (e. g. , an angioscope). The incorporated endoscope is useable to A) visually locate side branches which emanate from the anatomical passageway and b) visually observe the operation of the side branch blocking apparatus. Also disclosed are methods for utilizing a device of the forgoing character, including methods for performing in situ embolization of the side branches of a vein, under angioscopic visualization. The endoscopic component of the device may also be utilized to visually observe the use and/or effect of one or more separate device, such as valvulotome(s) used for cutting venous valves located within the lumen of a vein.

US Patent:

61789682, Jan 30, 2001

Filed:

May 7, 1999

Appl. No.:

9/306863

Inventors:

Frank Louw - Carlsbad CA
Stephen A. Sosnowski - Oceanside CA
David Rosenthal - Marietta GA

Assignee:

Edwards Lifesciences Corp. - Irvine CA

International Classification:

A61M 2900
A61M 2500
A61B 100

US Classification:

128898

Abstract:

Methods for utilizing a device for blocking (e. g. , embolizing) the side branches of an anatomical passageway under endoscopic guidance. The device comprises an elongate catheter body having a side branch blocking apparatus, such as an embolization catheter, disposed therein and further incorporating an endoscope (e. g. , an angioscope). The incorporated endoscope is useable to a) visually locate side branches which emanate from the anatomical passageway and b) visually observe the operation of the side branch blocking apparatus. Disclosed are methods for performing in situ embolization of the side branches of a vein, under angioscopic visualization. The endoscopic component of the device may also be utilized to visually observe the use and/or effect of one or more separate device, such as valvulotome(s) used for cutting venous valves located within the lumen of a vein.

US Patent:

D2695472, Jun 28, 1983

Filed:

Jul 16, 1981

Appl. No.:

6/284075

Inventors:

David B. Rosenthal - Jamaica NY

International Classification:

D2402

US Classification:

D24 26

US Patent:

59479949, Sep 7, 1999

Filed:

Aug 8, 1997

Appl. No.:

8/910944

Inventors:

Frank Louw - Carlsbad CA
Stephen A. Sosnowski - Oceanside CA
David Rosenthal - Marietta GA

Assignee:

Baxter International Inc. - Deerfield IL

International Classification:

A61B 2900

US Classification:

606200

Abstract:

The device for blocking (e. g. , embolizing) the side branches of an anatomical passageway under endoscopic guidance. The device comprises an elongate catheter body having a side branch blocking apparatus, such as an embolization catheter, disposed therein and further incorporating an endoscope (e. g. , an angioscope). The incorporated endoscope is useable to A) visually locate side branches which emanate from the anatomical passageway and b) visually observe the operation of the side branch blocking apparatus. Also disclosed are methods for utilizing a device of the forgoing character, including methods for performing in situ embolization of the side branches of a vein, under angioscopic visualization. The endoscopic component of the device may also be utilized to visually observe the use and/or effect of one or more separate device, such as valvulotome(s) used for cutting venous valves located within the lumen of a vein.