David Randall Roth

US Patent:

7604995, Oct 20, 2009

Filed:

Jul 9, 2004

Appl. No.:

10/887593

Inventors:

David B. Roth - New York NY, US
Gregory S. Lee - New York NY, US

Assignee:

New York University - New York NY

International Classification:

C12N 15/87
C12N 15/00
C12N 15/64
C12P 19/34

US Classification:

435463, 435455, 435 914, 435 911

Abstract:

A method of stimulating homologous recombination by creating at least one nick in a targeted polynucleotide sequence. Wherein nonhomologous recombination is suppressed resulting in increasing the ratio of targeted to nontargeted events. A method of increasing double strand break-initiated gene targeting by inducing a nick in a targeted polynucleotide sequence, wherein overall recombination levels are increased. A method of increasing homologous recombination employing a recombinase that releases the ends in living cells by stimulating homolgous recombination to higher levels than those attainable with standard nucleases. A composition for stimulating homologous recombination including a nicking mechanism for creating nicks in a polynucleotide, wherein the nicking mechanism stimulates homologous recombination. A composition for stimulating homologous recombination including a nicking endonucleases. Various kits for stimulating homologous recombination.

US Patent:

8364541, Jan 29, 2013

Filed:

Oct 29, 2007

Appl. No.:

11/926939

Inventors:

David William Roth - San Francisco CA, US

Assignee:

BEH Investments LLC - Brooklyn NY

International Classification:

G06Q 30/00

US Classification:

705 1471, 705 37, 705 1423, 705 263

Abstract:

A method implemented in a computer system for determining an advertisement in response to an advertising opportunity, wherein the advertising opportunity is an opportunity to place the advertisement on a web page subsequent to a request for the web page by a browser. The computer system receives an indication of the advertising opportunity, and in response to receiving the indication, the computer system determines bids, wherein each bid is associated with an advertisement, selects one of the bids and places the advertisement associated with the selected bid on the web page.

US Patent:

8447581, May 21, 2013

Filed:

Sep 15, 2009

Appl. No.:

12/559847

Inventors:

David Roth - San Francisco CA, US
Hem C. Neema - Sunnyvale CA, US

Assignee:

Xilinx, Inc. - San Jose CA

International Classification:

G06F 17/50

US Classification:

703 14, 716104

Abstract:

During the elaboration and synthesis of a circuit design, a parse tree generally must be fully expanded to access memory resources and data of individual module instances in order to perform optimizations that will result in better runtime performance of generated simulation code. The present invention reduces memory requirements in generating simulation or emulation executable code by implementing a collapsed parse tree, where multiple instances of a module in a HDL design are represented by a single representative node in the parse tree.

US Patent:

20020029186, Mar 7, 2002

Filed:

Aug 10, 2001

Appl. No.:

09/927981

Inventors:

David Roth - San Francisco CA, US
Dylan Salisbury - San Francisco CA, US

International Classification:

G06F017/60

US Classification:

705/037000, 705/014000

Abstract:

A system for providing advertisements from a central server to viewers who access web sites. The central server stores both advertisements which are to be displayed and an information data base. The data base includes information about viewers, information about the characteristics of particular web sites and other information relevant to which advertisements should be displayed for particular viewers. Proposed bids submitted by different advertisers are evaluated in real time in order to determine which particular advertisement will be displayed to a viewer. Each proposed bid can specify a price or amount that the advertiser is willing to pay for the opportunity to display an advertisement (a) to a viewer who has a particular set of characteristics and (b) on a web site and web page that meets a particular set of criteria. The system includes (a) a web server system which has data bases stored therein, (b) bidding agents which compare the characteristics of view-ops to the specifications in proposed bids and which submit bids as appropriate, and (c) bid selection logic which decides which bid to accept for each particular view-op.

US Patent:

20050154742, Jul 14, 2005

Filed:

Nov 24, 2004

Appl. No.:

10/996792

Inventors:

Aviv Roth - Brooklyn NY, US
David Roth - New York NY, US

International Classification:

G06F007/00

US Classification:

707100000

Abstract:

A business software application generation system and method are described.

US Patent:

20070299682, Dec 27, 2007

Filed:

Feb 15, 2007

Appl. No.:

11/675429

Inventors:

David Roth - San Francisco CA, US
Dylan Salisbury - Morgan Hill CA, US

International Classification:

G06Q 30/00

US Classification:

705001000

Abstract:

A method implemented in a computer system for determining an advertisement in response to an advertising opportunity, wherein the advertising opportunity is an opportunity to place the advertisement on a web page subsequent to a request for the web page by a browser. The computer system receives an indication of the advertising opportunity, and in response to receiving the indication, the computer system determines one or more bids, wherein each bid is associated with an advertisement; selects a bid from among the one or more bids; and places the advertisement associated with the selected bid on the web page.

US Patent:

20080059361, Mar 6, 2008

Filed:

Oct 31, 2007

Appl. No.:

11/933080

Inventors:

David Roth - San Francisco CA, US
Dylan Salisbury - Morgan Hill CA, US

International Classification:

G06Q 40/00
G06F 17/30
G06F 17/40

US Classification:

705037000

Abstract:

A method implemented in a computer system for determining an advertisement in response to an advertising opportunity, wherein the advertising opportunity is an opportunity to place the advertisement on a web page subsequent to a request for the web page by a browser. The computer system receives an indication of the advertising opportunity, and in response to receiving the indication, the computer system determines bids, wherein each bid is associated with an advertisement, selects one of the bids and places the advertisement associated with the selected bid on the web page.

US Patent:

20080059362, Mar 6, 2008

Filed:

Oct 31, 2007

Appl. No.:

11/933122

Inventors:

David Roth - San Francisco CA, US
Dylan Salisbury - Morgan Hill CA, US

International Classification:

G06Q 40/00
G06F 17/30
G06F 17/40

US Classification:

705037000

Abstract:

A method implemented in a computer system for determining an advertisement in response to an advertising opportunity, wherein the advertising opportunity is an opportunity to place the advertisement on a web page subsequent to a request for the web page by a browser. The computer system receives an indication of the advertising opportunity, and in response to receiving the indication, the computer system determines bids, wherein each bid is associated with an advertisement, selects one of the bids and places the advertisement associated with the selected bid on the web page.