David I Scheer

US Patent:

60018402, Dec 14, 1999

Filed:

Feb 19, 1993

Appl. No.:

8/020220

Inventors:

John A. Montgomery - Birmingham AL
John A. Secrist - Birmingham AL
L. Lee Bennett - Birmingham AL
William B. Parker - Birmingham AL
Y. Fumer Shealy - Birmingham AL
David I. Scheer - Guilford CT

Assignee:

Southern Research Institute - Birmingham AL

International Classification:

A61K 3152

US Classification:

514261

Abstract:

Method for prophylaxis and treatment of a viral infection characterized by the administration of a composition comprising a substantial molar excess of the D-stereoisomer of 2'CdG over the L-stereoisomer.

US Patent:

59121742, Jun 15, 1999

Filed:

Nov 20, 1995

Appl. No.:

8/559894

Inventors:

David Scheer - Guilford CT
Bernard M. Babior - San Diego CA

International Classification:

C12N 500
A61K 3514

US Classification:

435374

Abstract:

Methods of stabilizing lymphocytes and/or stem cells obtained from a mammal by suspending them in an aqueous medium comprising gelatin.

US Patent:

60807466, Jun 27, 2000

Filed:

Oct 16, 1991

Appl. No.:

7/776895

Inventors:

David I. Scheer - Branford CT

International Classification:

A61K 716
A61K 7035
A61K 742

US Classification:

514258

Abstract:

Methods and compositions for preventing or treating cytomegalovirus infections by the use of carbocyclic analogues of purine and pyrimidine nucleosides.

US Patent:

50194020, May 28, 1991

Filed:

Feb 20, 1990

Appl. No.:

7/483205

Inventors:

Robert D. Kross - Bellmore NY
David I. Scheer - Guilford CT

Assignee:

Alcide Corporation - Norwalk CT

International Classification:

A61K 3516

US Classification:

424665

Abstract:

There is disclosed a composition and process for disinfecting or essentially sterilizing blood fractions and components of blood. The composition is formed by adding a chlorine dioxide liberating compound with a weak organic acid and a heat activated saccharide.

US Patent:

52100960, May 11, 1993

Filed:

Jul 10, 1991

Appl. No.:

7/728896

Inventors:

David I. Scheer - Guilford CT

Assignee:

Chai-Tech Corporation - Greenvale NY

International Classification:

A61K 34295

US Classification:

514501

Abstract:

Compositions having significant activity as antiviral agent are disclosed containing, as an active component, a compound having the structural formula: ##STR1## wherein R. sub. 1 and R. sub. 1' are the same or different and each is an alkyl group, a phenyl group or a substituted derivative of a phenyl group; wherein R. sub. 2 and R. sub. 2' are the same or different and each is hydrogen, an unbranched alkyl group, a halide or a group having the structure ##STR2## wherein R is hydrogen, an alkoxide group, an alkyl group, or OH; wherein R. sub. 3 and R. sub. 3' are the same or different and each is hydrogen or an alkyl group; wherein X and X' are the same or different and each is a water soluble group having weak to intermediate ligand field strength; and Q. sup. - is a soluble, pharmaceutically acceptable negative ion. Methods of use of the inventive compositions are also disclosed.

US Patent:

48575143, Aug 15, 1989

Filed:

Sep 17, 1985

Appl. No.:

6/776918

Inventors:

Arnold S. Lippa - Franklin Lakes NJ
David I. Scheer - Branford CT

Assignee:

Yeda Research and Development Company, Ltd. - Rehovot

International Classification:

A61K 31685

US Classification:

514 78

Abstract:

A virus having a lipid-containing capsid, such as AIDS virus, is inactivated by contacting the virus with an inactivating amount of phosphatidyl choline. Such a virus can be inactivated in fluids such as virus-contaminated body fluids or derivatives, e. g. , blood or blood derivatives. The phosphatidyl choline can be present in an Active Lipid (AL) composition further comprising neutral lipids and phosphatidyl ethanolamine. Phosphatidyl choline, and an AL composition containing same, is useful for the treatment or prophylaxis of Acquired Immune Deficiency Syndrome (AIDS) in mammals.

US Patent:

51068419, Apr 21, 1992

Filed:

Mar 30, 1990

Appl. No.:

7/502294

Inventors:

David I. Scheer - Guilford CT

Assignee:

Chai-Tech Corporation - Greenvale NY

International Classification:

A61K 3133
A61K 31555

US Classification:

514185

Abstract:

Compositions having significant activity as antiviral agent are disclosed containing, as an active component, a compound having the structural formula: ##STR1## wherein R. sub. 1 and R. sub. 1' are the same or different and each is an alkyl group, a phenyl group or a substituted derivative of a phenyl group; wherein R. sub. 2 and R. sub. 2' are the same or different and each is hydrogen, an unbranched alkyl group, a halide or a group having the structure ##STR2## wherein R is hydrogen, an alkoxide group, an alkyl group, or OH; wherein R. sub. 3 and R. sub. 3' are the same or different and each is hydrogen or an alkyl group; wherein X and X' are the same or different and each is a water soluble group having weak to intermediate ligand field strength; and Q. sup. - is a soluble, pharmaceutically acceptable negative ion. Methods of use of the inventive compositions are also disclosed.