David C Silver

US Patent:

8129121, Mar 6, 2012

Filed:

Jan 8, 2008

Appl. No.:

12/448840

Inventors:

David L. Silver - New York NY, US

Assignee:

Albert Einstein College of Medicine of Yeshiva University - Bronx NY
The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/68
A61K 51/00
C12N 15/11

US Classification:

435 613, 514 44 A, 424 165

Abstract:

This invention provides methods of regulating fat storage in tissue by modulating the levels of Fibrate Induced Transcript 1 (FIT1) and/or Fibrate Induced Transcript 2 (FIT2), as well as diagnostic screens for disorders and conditions involving regulation of fat storage in tissue, assays for identifying agents that can regulate fat storage in tissue through modulating the levels of FIT1 and/or FIT2, and genetically altered mammals in which expression of FIT1 and/or FIT2 is altered in one or more tissue.

US Patent:

20040096851, May 20, 2004

Filed:

Apr 28, 2003

Appl. No.:

10/425406

Inventors:

Nan Wang - Flushing NY, US
Alan Tall - Creskil NJ, US
David Silver - New York NY, US

International Classification:

C12Q001/68
G01N033/53
C07H021/04
C07K014/705

US Classification:

435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500

Abstract:

This invention provides an isolated ABCA1 protein having a mutation within its PEST domain. This invention also provides related nucleic acids, vectors, host cells, pharmaceutical compositions and articles of manufacture. This invention further provides methods for determining whether a protease inhibitor increases the rate of cholesterol efflux from a cell, for increasing ABCA1-mediated cholesterol efflux from a cell, for treating atherosclerosis in a subject, and for increasing HDL formation in a subject.

US Patent:

62928376, Sep 18, 2001

Filed:

Oct 30, 1998

Appl. No.:

9/182996

Inventors:

Daniel Miller - New York NY
David Silver - New York NY
Neil Radisch - New York NY
Michael Stenzler - New York NY
Gerry Rossi - Ridgewood NJ

International Classification:

G06F 1516

US Classification:

709236

Abstract:

An apparatus and method for image display and transmission, including display and transmission of data over the Internet. Image transmission is effected by non-sequential streaming of sequential images or of multiple views of a scene or object. The present invention sends image frames from server to browser out of order. Wherever the cursor is positioned, the browser displays the nearest frame which is received from the server. The viewer, therefore, is able to see more sides of the image without waiting for the entire image to be transmitted.

US Patent:

43849440, May 24, 1983

Filed:

Sep 3, 1981

Appl. No.:

6/299038

Inventors:

David A. Silver - Livingston NJ
Rudolf G. Lukac - East Brunswick NJ
Solomon Rubinstein - Fanwood NJ

Assignee:

Pirelli Cable Corporation - Union NJ

International Classification:

B32B 2716
C08J 328

US Classification:

20415913

Abstract:

Insulation for an electric power cable, and a power cable including such insulation, the insulation having an improved dielectric strength and being irradiation cross-linked polymeric material having mixed therewith carbon black having a particle size in the range from about 200 to about 500 millimicrons, the carbon black content being about 10% to about 40% of the weight of the mixture of carbon black and the polymeric material. Also, the cable insulation may be layers of different density polyethylene, at least one of the layers being the described mixture of polyethylene and carbon black.

US Patent:

45854076, Apr 29, 1986

Filed:

Oct 3, 1983

Appl. No.:

6/538590

Inventors:

David A. Silver - Livingston NJ
John C. Rowland - Westfield NJ

Assignee:

Pirelli Cable Corporation - Union NJ

International Classification:

B29C 4702
B29C 4704

US Classification:

425114

Abstract:

Apparatus for extruding a first layer of a semi-conductive plastic material around the conductor of an electric power cable and for extruding a second layer of plastic insulating material around the first layer as the conductor is advanced in which the extruder for the insulating material includes an extrusion head which comprises a body with a passageway therethrough for the passage of the conductor through the body and having at least one channel therein extending from the exterior thereof to adjacent one end of the passageway for supplying the insulated material around the conductor. An extrusion tip or tubular guide is disposed in the passageway for guiding said conductor and extends across part of the channel for contacting material exiting from the channel. The guide comprises a ceramic tube with a polished inner surface forming the innermost surface of the guide.

US Patent:

61083836, Aug 22, 2000

Filed:

Jul 15, 1998

Appl. No.:

9/115895

Inventors:

Daniel Miller - New York NY
Timothy S. Murphy - New York NY
Blake Sloan - Woodstock NY
David Silver - New York NY
Eric Ameres - Cohoes NY

Assignee:

On2.com, Inc. - New York NY

International Classification:

H04N 726

US Classification:

375240

Abstract:

This invention uses a novel synthesis of several different compression methods, some original and some known in the art, to achieve compression of digitized video image sequences. Images are color-reduced by a factor of two in both directions using a colorspace that requires minimal computation for reconstruction of RGB pixel values. Images are then transformed into a `token sequence` corresponding to a series of 4. times. 4 blocks, using one of seven transformation methods, some dependent on previous frames and some dependent only on pixel values in neighboring blocks. The resulting token sequence is then compressed using known lossless methods, including Huffman coding.

US Patent:

47835761, Nov 8, 1988

Filed:

Oct 1, 1987

Appl. No.:

7/103826

Inventors:

David A. Silver - Livingston NJ
William G. Lawson - Summit NJ

Assignee:

Pirelli Cable Corporation - Union NJ

International Classification:

H01B 702

US Classification:

174 25R

Abstract:

A high voltage, gas filled, pipe type electrical cable and method of manufacture thereof. The cable comprises a plurality of insulated conductors, each conductor having a central gas passageway and being gas permeable. The conductor is wrapped with tapes impregnated with an insulating oil, and the wrapped tapes are encircled by gas permeable layers and skid wires. Three of such insulated conductors are encircled by a gas impermeable pipe, and the pipe and the conductor passageways are filled with an insulating gas under pressure above atmospheric pressure so that both the interior and exterior surfaces of the wrapped tapes are subjected to such gas. Preferably, the gas is a mixture of sulfur hexafluoride and nitrogen at a pressure of at least 200 psig. The tapes are impregnated with the oil and drained before they are wrapped around the conductor so as to provide gaps between the tapes which are substantially filled with the gas.

US Patent:

43755771, Mar 1, 1983

Filed:

Jan 5, 1981

Appl. No.:

6/222639

Inventors:

David A. Silver - Livingston NJ
Attila F. Dima - Piscataway NJ
George W. Seman - Piscataway NJ

Assignee:

Pirelli Cable Corporation - Union NJ

International Classification:

H02G 1525

US Classification:

174 22R

Abstract:

A stop joint for a pair of electric cables having fluid under pressure therein in which the fluid impermeable pipe or shield around the cable, which is spaced at its end from the bared conductor end to expose the cable insulation, is connected to the connector for interconnecting the cable ends by a multi-part stop tube having an intermediate portion of insulating material and a pair of end portions bonded to respective ends of the intermediate portion, the end portions being made of an insulating material rendered conductive by the addition of conductive material or of insulating material having a conductive layer thereon for forming electrodes for electrical stress distribution purposes. The electrodes have substantially the same coefficient of expansion as the material of the intermediate tube portion to prevent separation of the end portions from the intermediate portion with temperature changes.