Dean David Erdman

US Patent:

7776521, Aug 17, 2010

Filed:

May 14, 2007

Appl. No.:

11/748359

Inventors:

Paul A. Rota - Decatur GA, US
Larry J. Anderson - Atlanta GA, US
William J. Bellini - Lilburn GA, US
Michael D. Bowen - Decatur GA, US
Cara Carthel Burns - Avondale Estates GA, US
Raymond Campagnoli - Decatur GA, US
Qi Chen - Marietta GA, US
James A. Comer - Decatur GA, US
Byron T. Cook - Augusta GA, US
Shannon L. Emery - Lusaka, ZM
Dean D. Erdman - Decatur GA, US
Cynthia S. Goldsmith - Lilburn GA, US
Jeanette Guarner - Decatur GA, US
Charles D. Humphrey - Lilburn GA, US
Joseph P. Icenogle - Atlanta GA, US
Thomas G. Ksiazek - Lilburn GA, US
Richard F. Meyer - Roswell GA, US
Stephan S. Monroe - Decatur GA, US
William Allan Nix - Bethlehem GA, US
M. Steven Oberste - Lilburn GA, US
Christopher D. Paddock - Atlanta GA, US
Teresa C. T. Peret - Atlanta GA, US
Pierre E. Rollin - Lilburn GA, US
Mark A. Pallansch - Lilburn GA, US
Anthony Sanchez - Lilburn GA, US
Wun-Ju Shieh - Norcross GA, US
Suxiang Tong - Alpharetta GA, US
Sherif R. Zaki - Atlanta GA, US

Assignee:

The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention - Washington DC

International Classification:

C12Q 1/70
C07H 21/00
C12N 15/50

US Classification:

435 5, 536 2432, 536 2433

Abstract:

Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use.

US Patent:

20100143881, Jun 10, 2010

Filed:

Dec 5, 2008

Appl. No.:

12/315758

Inventors:

Xiaoyan Lu - Atlanta GA, US
Dean Erdman - Decatur GA, US

International Classification:

C12Q 1/70
C07H 21/04

US Classification:

435 5, 536 2372

Abstract:

A process for detecting human rhinovirus nucleic acid in a biological sample, includes producing an amplification product by amplifying an human bocavirus nucleotide sequence using a forward primer of SEQ ID NO: 1, and a reverse primer of SEQ ID NO: 2, and measuring said amplification product to detect human rhinovirus in said biological sample. Also provided are reagents and methods for detecting and distinguishing human rhinovirus from other viruses. A kit is provided for detecting and quantifying human rhinovirus in a biological sample.

US Patent:

20110014723, Jan 20, 2011

Filed:

Mar 13, 2009

Appl. No.:

12/922364

Inventors:

Dean D. Erdman - Decatur GA, US
Teresa Peret - Atlanta GA, US

International Classification:

G01N 33/53
C12P 21/00
C07K 14/005

US Classification:

436501, 435 691, 530350

Abstract:

Non-replicating, antigenic, human bocavirus virus-like particles (HBoV VLPs) are provided by the present invention along with assays using the HBoV VLPs to detect anti-HBoV antibodies in a biological sample. Pharmaceutical compositions including HBoV VLPs and/or anti-HBoV antibodies are described herein along with novel antibodies generated using HBoV VLPs as an antigen. A recombinant baculovirus is provided including a DNA sequence encoding an expressible human bocavirus VP2 with or without a DNA sequence encoding an expressible human bocavirus VP1 polypeptide, and/or a non-HBoV peptide or protein, and culturing the cells to form the VP1 and/or VP2 proteins that self assemble to form the HBoV VLPs which are then amenable to isolation.

US Patent:

7220852, May 22, 2007

Filed:

Apr 12, 2004

Appl. No.:

10/822904

Inventors:

Paul A. Rota - Decatur GA, US
Larry J. Anderson - Atlanta GA, US
William J. Bellini - Lilburn GA, US
Cara Carthel Burns - Avondale Estates GA, US
Raymond Campagnoli - Decatur GA, US
Qi Chen - Marietta GA, US
James A. Comer - Decatur GA, US
Shannon L. Emery - Lusaka, ZM
Dean D. Erdman - Decatur GA, US
Cynthia S. Goldsmith - Lilburn GA, US
Charles D. Humphrey - Lilburn GA, US
Joseph P. Icenogle - Atlanta GA, US
Thomas G. Ksiazek - Lilburn GA, US
Stephan S. Monroe - Decatur GA, US
William Allan Nix - Bethlehem GA, US
M. Steven Oberste - Lilburn GA, US
Teresa C. T. Peret - Atlanta GA, US
Pierre E. Rollin - Lilburn GA, US
Mark A. Pallansch - Lilburn GA, US
Anthony Sanchez - Lilburn GA, US
Suxiang Tong - Alpharetta GA, US
Sherif R. Zaki - Atlanta GA, US

Assignee:

The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention - Washington DC

International Classification:

C12N 15/50
C12N 7/00

US Classification:

536 2372, 4352351

Abstract:

Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use.

US Patent:

20150099263, Apr 9, 2015

Filed:

Dec 15, 2014

Appl. No.:

14/570569

Inventors:

- Rockville MD, US
Dean D. Erdman - Decatur GA, US

International Classification:

C12Q 1/70

US Classification:

435 5

Abstract:

A process for detecting human rhinovirus nucleic acid in a biological sample, includes producing an amplification product by amplifying an human bocavirus nucleotide sequence using a forward primer of SEQ ID NO: 1, and a reverse primer of SEQ ID NO: 2, and measuring said amplification product to detect human rhinovirus in said biological sample. Also provided are reagents and methods for detecting and distinguishing human rhinovirus from other viruses. A kit is provided for detecting and quantifying human rhinovirus in a biological sample.