Deborah Ann Dean

US Patent:

8309102, Nov 13, 2012

Filed:

May 11, 2011

Appl. No.:

13/105676

Inventors:

Randall J. Mrsny - Los Altos Hills CA, US
Deborah Dean - San Anselmo CA, US

Assignee:

Children's Hospital and Research Center at Oakland - Oakland CA

International Classification:

A61K 39/118
C12P 21/04

US Classification:

4242631, 4241921, 435 697

Abstract:

The present invention relates, in part, to methods and compositions for immunizing against infection by. The methods and compositions rely, in part, on administering an immunogenic composition comprising one or more peptides derived from major outer membrane protein (MOMP) to a subject to be immunized. In some embodiments, the compositions comprise a chimeric immunogens, expression vectors comprising the polynucleotides, and kits comprising the compositions are also provided.

US Patent:

20090214570, Aug 27, 2009

Filed:

May 17, 2006

Appl. No.:

11/914734

Inventors:

Randall J. Mrsny - Los Altos Hills CA, US
Deborah Dean - San Anselmo CA, US

Assignee:

Trinity Biosystems, Inc. - Menlo Park CA
Children's Hospital & Research Center at Oakland - Oakland CA

International Classification:

A61K 39/395
C07K 14/00
C07K 16/00
C07K 14/475
C07K 14/54
C07H 21/00
C07K 7/08
A61P 31/04
A61P 37/04
C07K 7/06
C07K 14/295
C12N 15/63
C12N 1/00
C12P 21/00
A61K 39/118

US Classification:

4241641, 530350, 5303911, 530399, 530351, 536 234, 4353201, 435243, 435 693, 4241921, 530324, 530328, 530326, 530327

Abstract:

The present invention relates, in part, to methods and compositions for immunizing against infection by . The methods and compositions rely, in part, on administering an immunogenic composition comprising one or more peptides derived from major outer membrane protein (MOMP) to a subject to be immunized. In some embodiments, the compositions comprise a chimeric immunogen comprising a receptor binding domain, a translocation domain, and a antigen. Polynucleotides encoding the chimeric immunogens, expression vectors comprising the polynucleotides, and kits comprising the compositions are also provided.