Diane B Kebles

US Patent:

43584365, Nov 9, 1982

Filed:

Jun 9, 1980

Appl. No.:

6/155322

Inventors:

Henry A. Graham - Annandale NJ
David J. Olekna - Annandale NJ
Johnna B. Hawk - Rocky Hill NJ
Diane B. Kebles - Stewartsville NJ

Assignee:

Ortho Diagnostics, Inc. - Raritan NJ

International Classification:

G01N 3380

US Classification:

424 11

Abstract:

Methods and reagents for determination of Rh. sub. o (D), C, c, E, e, and K antigens in human blood. The reagents are low-protein compositions containing reduced and S-alkylated IgG antibody to the selected antigen maintained at a pH of between about 7. 5 and 8. 3. These reagents meet or exceed FDA standards for potency and specificity of the respective antisera.