Richard C Cannon

US Patent:

20070154569, Jul 5, 2007

Filed:

Jul 9, 2004

Appl. No.:

10/563683

Inventors:

Mark Gladwin - Washington DC, US
Alan Schechter - Bethesda MD, US
David Lefer - Bronx NY, US
Rakesh Patel - Birmingham AL, US
Christian Hunter - Bethesda MD, US
Gordon Power - Redlands CA, US
Daniel Kim-Shapiro - Winston-Salem NC, US
Ryszard Pluta - Bethesda MD, US
Edward Oldfield - Philomont VA, US
Richard Cannon - Potomac MD, US

Assignee:

The Govt. of the U.S.A. through The Dept. of Health and Human Services - Rockville MD
The University of Alabama Research Foundation - Birmingham AL
Wake Forest University - Winston-Salem NC
Loma Linda University - Loma Linda CA
The Board of Supervisors of Louisiana State University - Shreveport LA

International Classification:

A61K 33/00
A61P 9/00
A01N 59/00
A61P 11/00

US Classification:

424718000

Abstract:

It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension. This discovery provides useful treatments to regulate a subject's blood pressure and blood flow, for example, by the administration of nitrite salts. Provided herein are methods of administering a pharmaceutically-acceptable nitrite salt to a subject, for treating, preventing or ameliorating a condition selected from: (a) ischemia-reperfusion injury (e.g., hepatic or cardiac or brain ischemia-reperfusion injury); (b) pulmonary hypertension (e.g., neonatal pulmonary hypertension); or (c) cerebral artery vasospasm.

US Patent:

48673102, Sep 19, 1989

Filed:

Aug 11, 1987

Appl. No.:

7/084694

Inventors:

Richard K. Cannon - San Francisco CA
Robert S. Jaret - San Francisco CA

International Classification:

B65D 85672

US Classification:

206387

Abstract:

A disposable cassette tape holder for securing a cassette tape to a file jacket or document is formed from a single sheet of pliable material having two parallel fold lines which define a front, back and fold panels of the holder. The front and back panels of the holder are folded about the fold lines to form a cassette tape holding pocket and, in one embodiment, the cassette tape is releasably held in the holding pocket, and the holder is in turn secured to the file jacket or document, by a light adhesive applied to the panels of the holder. Depending on the placement of the adhesive, the holder can be adhered directly to the top of a file jacket or document, or the file jacket or document can be interleaved between the holder's back panel and the held cassette tape. In another version of cassette tape holder of the invention the holder is fabricated of a semi-rigid sheet of plastic or metal material having front and back panels prefolded together to a sufficient closure to require the panels to be pried open to insert a cassette tape. In yet another version of the invention a foldable holder is formed as an integral extension of a file jacket.