Dilip M Shah

US Patent:

6355161, Mar 12, 2002

Filed:

Apr 14, 2000

Appl. No.:

09/549897

Inventors:

Dilip H. Shah - Buffalo Grove IL
Gary Howell - Elkton MD
Kenneth E. Pawlak - Vernon Hills IL
Masatoshi Ozono - Tokyo, JP
Wade Fournier - Spring Grove IL
Mete Alpan - LaGrange IL

Assignee:

Aksys, Ltd. - Lincolnshire IL
Teijin, Ltd. - Osaka

International Classification:

B01D 6128

US Classification:

210 91, 21032171, 210647, 206570, 2064591, 2064595, 215382, 220669

Abstract:

A set of bottles for containing dialysate chemical formulations, chemical cleaning agents or the like is described. The chemical formulation bottles come in two varieties, sodium bicarbonate and liquid acid formulations, each bottle having a slightly different shape. The different shapes cooperate with a bottle mounting structure in the dialysis machine to insure that bottles are correctly installed on their respective bottle opening mechanism. The bottles also have a detection feature comprising either a raised rim or groove extending around the periphery of the bottle. A sensor assembly in the bottle mounting and opening system detects the detection feature. The detection feature is used by the machine to distinguish between dialysate formulation bottles and chemical cleaning bottles, which do not have the detection feature. The detection feature prevents unintentional installation of the chemical bottle on the opening mechanism for the dialysate chemical formulation bottles. A chemical loading system for use with the bottles, and having a detection system for detecting the detection feature is also described.

US Patent:

7544301, Jun 9, 2009

Filed:

Aug 19, 2004

Appl. No.:

10/921677

Inventors:

Dilip H. Shah - Buffalo Grove IL, US
Todd Ing - Wilmette IL, US

Assignee:

HHD LLC - Manchester NH

International Classification:

B01D 61/26
B01D 61/24

US Classification:

210647, 21032171, 210646, 424600, 424663, 424678, 424680, 424681, 424686, 424717, 514574, 604 29

Abstract:

The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.

US Patent:

7790103, Sep 7, 2010

Filed:

Jul 5, 2007

Appl. No.:

11/773588

Inventors:

Dilip Shah - Buffalo Grove IL, US
Douglas Reitz - Green Oaks IL, US
Samuel Ding - Libertyville IL, US
Meir Dahan - Lincolnwood IL, US
Gino Cicchello - Vernon Hills IL, US
John A. Biewer - Palm Harbor FL, US

Assignee:

Baxter International Inc. - Deerfield IL
Baxter Healthcare S.A. - Glattpark (Opfikon)

International Classification:

A61L 2/00
A61L 2/18
A61L 9/00
A61L 2/20
B01J 7/00

US Classification:

422 28, 422 29, 422 33, 422305

Abstract:

A medical fluid machine, such as a dialysis machine, includes a pump that pumps a medical fluid and sterile water or other disinfecting liquid, such as ozonated water, for flushing and reconditioning the medical fluid machine. The machine may also include a heater that heats the medical fluid or disinfecting solution in order to kill bacteria and other microorganisms that may contaminate the machine after use. Disinfecting the machine, and a disposable kit used with the machine, may allow re-use of the disposable within a reasonable amount of time after completion of the disinfecting procedure. Dialysate treated with ultra-violet light or water with low concentrations of ozone also helps make the disposable kits suitable for reuse.

US Patent:

7883725, Feb 8, 2011

Filed:

May 29, 2009

Appl. No.:

12/474658

Inventors:

Dilip H. Shah - Buffalo Grove IL, US
Todd Ing - Wilmette IL, US

Assignee:

HHD LLC - Manchester NH

International Classification:

A61K 33/14
A61K 31/19
B01D 61/26
B01D 61/24

US Classification:

424600, 21032171, 210646, 210647, 424663, 424678, 424680, 424681, 424686, 424717, 514574, 604 29

Abstract:

The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.

US Patent:

8202547, Jun 19, 2012

Filed:

Jan 17, 2011

Appl. No.:

13/007863

Inventors:

Dilip H. Shah - Buffalo Grove IL, US
Todd Ing - Wilmette IL, US

Assignee:

Baxter International Inc. - Deerfield IL
Baxter Healthcare S.A. - Glattpark-Opfikon

International Classification:

A61K 33/14
A61K 31/19
B01D 61/26
B01D 61/24

US Classification:

424600, 424663, 424678, 424680, 424681, 424686, 424717, 514574

Abstract:

The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.

US Patent:

8414768, Apr 9, 2013

Filed:

Jun 11, 2012

Appl. No.:

13/493106

Inventors:

Dilip H. Shah - Buffalo Grove IL, US
Todd Ing - Wilmette IL, US

Assignee:

Baxter International Inc. - Deerfield IL
Baxter Healthcare S.A. - Glattpark-Opfikon

International Classification:

B01D 61/26
B01D 61/28
B01D 61/24

US Classification:

21032171, 210 85, 210 97, 210134, 210143, 210194, 2101952, 210252, 2102571, 2102572, 210258, 424600, 424663, 424678, 424680, 424681, 424686, 424717, 514574

Abstract:

The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.

US Patent:

61362018, Oct 24, 2000

Filed:

Nov 4, 1998

Appl. No.:

9/186501

Inventors:

Dilip H. Shah - Buffalo Grove IL
Derek Wiebenson - Palatine IL
Tom L. Brose - Gurnee IL
Shincy Maliekkal - Mt. Prospect IL

Assignee:

AKSYS, Ltd. - Lincolnshire IL

International Classification:

B01D 6100
B01D 6126

US Classification:

210739

Abstract:

A batch of dialysate solution is made from a mixture of bicarbonate formulation and a liquid acid formulation. The liquid acid formulation is introduced into a dialysate tank and then removed from the tank and stored elsewhere, such as in an ultrafiltration tank, where it is diluted with a few litres of water. The dialysate tank is then filled with water and the bicarbonate formulation is added to the dialysate tank. The bicarbonate formulation is mixed and dissolved by circulation in a closed loop, with the liquid acid formulation kept separate. When the bicarbonate solution has been prepared, the liquid acid solution and the bicarbonate solution are mixed together and stored in the dialysate preparation tank. An additional quantity of dilution water is introduced into the dialysate system to bring the final conductivity down to the desired range. The excess dialysate solution can be used for several purposes, such as an endotoxin flush of the blood tubing set or a dialyzer clearance test.

US Patent:

49352431, Jun 19, 1990

Filed:

Dec 19, 1988

Appl. No.:

7/286324

Inventors:

Lionel Borkan - New Vernon NJ
Ira R. Berry - Westfield NJ
Dilip Shah - Flanders NJ

Assignee:

Pharmacaps, Inc. - Elizabeth NJ

International Classification:

A61K 928

US Classification:

424441

Abstract:

In accordance with the present invention, there is provided a chewable, edible soft gelatin capsule which comprises a shell comprising water, gelatin, plasticizer, and an amount of hydrogenated starch hydrolysate effective to render said shell dispersible and soluble in the mouth of the user; and a soft gelatin capsule fill material in which an active ingredient, preferably a biologically-active agent, is dispersed or dissolved.