Dominick Anthony Vacante

US Patent:

8092429, Jan 10, 2012

Filed:

Nov 10, 2010

Appl. No.:

12/943526

Inventors:

Mehdi Gasmi - San Diego CA, US
Elias T. Ketchum - La Mesa CA, US
Dominick A. Vacante - San Diego CA, US

Assignee:

Ceregene, Inc. - San Diego CA

International Classification:

A61M 5/178

US Classification:

60416401, 604158, 60416501, 600585

Abstract:

The needle assembly of the invention is a quad-partite system for use with an arc-center stereotactic headframe that allows a clinician to deliver recombinant expression vectors through the needle assembly to targeted sites at exact depths in the brain. Methods for use of the needle assembly with a rube insert for the needle cannula that does not bind proteins, as in protein viral capsids, permit delivery of precise volumes of pharmaceutical compositions containing viral recombinant expression vectors for gene therapy.

US Patent:

20080086061, Apr 10, 2008

Filed:

Oct 10, 2006

Appl. No.:

11/545609

Inventors:

Mehdi Gasmi - San Diego CA, US
Elias T. Ketchum - La Mesa CA, US
Dominick A. Vacante - San Diego CA, US

International Classification:

A61M 25/00
A61M 5/178

US Classification:

600585, 60416401

Abstract:

The needle assembly of the invention is a quad-partite system for use with an arc-center stereotactic headframe that allows a clinician to deliver recombinant expression vectors through the needle assembly to targeted sites at exact depths in the brain. Methods for use of the needle assembly with a tube insert for the needle cannula that does not bind proteins, as in protein viral capsids, permit delivery of precise volumes of pharmaceutical compositions containing viral recombinant expression vectors for gene therapy.