- Summit NJ, US John R. Coombs - New Brunswick NJ, US Keming Zhu - New Brunswick NJ, US Daniel Lim - Summit NJ, US Candice Lee Joe - New Brunswick NJ, US David T. George - New Brunswick NJ, US Bin Zheng - Kendall Park NJ, US Dong Lin - Monmouth Junction NJ, US
International Classification:
C07D 495/14 C07C 255/50 C07D 215/58 C07D 495/04
Abstract:
The present disclosure provides novel synthetic intermediates useful in the synthesis of MK2 kinase inhibitors.
Process For The Preparation Of 6-(Cyclopropaneamido)-4-((2-Methoxy-3-(1-Methyl-1H-1,2,4-Triazol-3-Yl)Phenyl)Amino)-N-(Methyl-D3)Pyridazine-3-Carboxamide
- Princeton NJ, US Joerg Deerberg - Columbus NJ, US Dong Lin - Monmouth Junction NJ, US Michael Dummeldinger - Plainsboro NJ, US Bahar Inankur - New Brunswick NJ, US Sergei Kolotuchin - Roselle Park NJ, US Jun Li - Langhorne PA, US Amanda J. Rogers - Asbury NJ, US Victor W. Rosso - Monroe Township NJ, US Eric M. Simmons - East Brunswick NJ, US Maxime C.D. Soumeillant - Princeton NJ, US Daniel S. Treitler - Cranford NJ, US Jianji Wang - Dayton NJ, US Bin Zheng - Kendall Park NJ, US Michael J. Smith - Somerset NJ, US Neil A. Strotman - Flemington NJ, US Steven Tymonko - Lindenhurst IL, US Tamas Benkovics - East Brunswick NJ, US
International Classification:
C07D 403/12 C07C 211/09 C07D 237/24 C07D 249/08
Abstract:
The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula:Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
Process For The Preparation Of 6-(Cyclopropaneamido)-4-((2-Methoxy-3-(1-Methyl-1H-1,2,4-Triazol-3-Yl)Phenyl)Amino)-N-(Methyl-D3)Pyridazine-3-Carboxamide
- Princeton NJ, US Joerg Deerberg - Columbus NJ, US Dong Lin - Monmouth Junction NJ, US Michael Dummeldinger - Plainsboro NJ, US Bahar Inankur - New Brunswick NJ, US Sergei Kolotuchin - Roselle Park NJ, US Jun Li - Langhorne PA, US Amanda J. Rogers - Asbury NJ, US Victor W. Rosso - Monroe Township NJ, US Eric M. Simmons - East Brunswick NJ, US Maxime C.D. Soumeillant - Princeton NJ, US Daniel S. Treitler - Cranford NJ, US Jianji Wang - Dayton NJ, US Bin Zheng - Kendall Park NJ, US Michael J. Smith - Somerset NJ, US Neil A. Strotman - Flemington NJ, US Steven Tymonko - Lindenhurst IL, US Tamas Benkovics - East Brunswick NJ, US
International Classification:
C07D 403/12 C07D 249/08 C07C 211/09 C07D 237/24
Abstract:
The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: [INSERT CHEMICAL STRUCTURE HERE] Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
Linkedin
Staff Software Engineer
Linkedin Jun 2016 - May 2018
Senior Software Engineer
The Apache Software Foundation Jun 2016 - May 2018
Kafka Committer and Pmc Member
Linkedin Apr 2015 - Jun 2016
Software Engineer
University of Pennsylvania Feb 2011 - Apr 2015
Research Assistant
Education:
University of Pennsylvania 2012 - 2015
University of Pennsylvania 2010 - 2012
Master of Science, Masters, Computer Science, Engineering
University of Pennsylvania 2010
Shanghai Jiao Tong University 2006 - 2010
Bachelors, Computer Science
Shanghai Jiao Tong University 2006
East China Normal University 2003 - 2006
East China Normal University 2003
Skills:
C++ Python Java Algorithms Research Distributed Systems Matlab C Computer Science Machine Learning Linux Sql Microsoft Office Latex Computer Vision Programming Javascript Html Microsoft Excel Eclipse Scala
Kaiser Permanente Medical GroupKaiser Permanente South San Francisco Medical Center 1200 El Camino Real, South San Francisco, CA 94080 (650)7422000 (phone), (650)7422606 (fax)
Dong Lin MD 950 Stockton St STE 207, San Francisco, CA 94108 (415)3999646 (phone), (415)3990156 (fax)
Education:
Medical School Beijing Med Univ, Beijing City, Beijing, China Graduated: 1982
Procedures:
Destruction of Benign/Premalignant Skin Lesions Hearing Evaluation Vaccine Administration
Dr. Lin graduated from the Beijing Med Univ, Beijing City, Beijing, China in 1982. He works in San Francisco, CA and 1 other location and specializes in Pediatrics. Dr. Lin is affiliated with California Pacific Medical Center California Campus, Kaiser Permanente Medical Center and UCSF Medical Center Parnassus.