Rocky Mountain Foot & Ankle Center 7615 W 38 Ave UNIT B101, Wheat Ridge, CO 80033 (303)4232520 (phone), (303)4232536 (fax)
Procedures:
Hallux Valgus Repair
Conditions:
Hallux Valgus Plantar Fascitis Tinea Pedis
Languages:
English Spanish
Description:
Dr. Kruse works in Wheat Ridge, CO and specializes in Podiatric Medicine. Dr. Kruse is affiliated with Lutheran Medical Center and St Anthony Hospital.
Us Patents
Methods, Compositions And Device For Directed And Controlled Heating And Release Of Agents
Dustin E. Kruse - Woodland CA, US Claude Meares - Davis CA, US Katherine W. Ferrara - Davis CA, US Eric Paoli - Los Altos CA, US Douglas N. Stephens - Davis CA, US Jeffrey Day - , US
International Classification:
A61K 9/127 A61N 7/02
US Classification:
424450, 601 3
Abstract:
A composition coupled to an agent with a cleavable linker is provided. Specifically, the composition is used for releasing the agent through a temperature-sensitive mechanism at a targeted location in a subject with heat. It is advantageous to applications where there is a need to accurately deploy an agent in a targeted location to reduce adverse side effects or increase efficacy of the agent. A device and method for providing heat at the targeted location in the subject is also provided. The device and method allows release of the agents in a targeted manner and prevents overheating of the targeted location or the tissue surrounding the targeted location. It is advantageous to applications where there is a need to accurately control the temperature in a targeted location in a biological body, for instance, to deploy an agent in the targeted location.