Edmund R Burke

US Patent:

20130165384, Jun 27, 2013

Filed:

Dec 14, 2012

Appl. No.:

13/694586

Inventors:

Edmund Burke - Jersey City NJ, US

International Classification:

A61K 38/39
A61K 38/17

US Classification:

514 172

Abstract:

A process for producing a decellularized small particle tissue which involves selecting an appropriate tissue starting material from which a decellularized small particle tissue is desired to be prepared, treating the tissue with a decellularizing agent at an acid pH to remove at least a portion of the cellular material therefrom and to yield a product comprising a liquid component and a solid component, subjecting the liquid component and the solid component to a plurality of filters, Fthrough F, wherein n may be 2, or an integer higher than 2, wherein the pore sizes of the filter Fthrough Frange from 200 microns to 10 Kilo Daltons, yielding filtrates and resonates, recycling either of said filtrates or said retentates or both, either separately or together, to any of steps b) or c) or both, at least one time, and isolating a decellularized small particle tissue from any of steps of the process. Both the product and process are novel.

US Patent:

20130288973, Oct 31, 2013

Filed:

Jun 20, 2013

Appl. No.:

13/986970

Inventors:

Edmund Burke - Jersey City NJ, US

International Classification:

A61K 35/12

US Classification:

514 172

Abstract:

A process for producing a decellularized small particle tissue which involves selecting an appropriate tissue starting material from which a decellularized small particle tissue is desired to be prepared, treating the tissue with a decellularizing agent at an acid pH to remove at least a portion of the cellular material therefrom and to yield a product comprising a liquid component and a solid component, subjecting the liquid component and the solid component to a plurality of filters, Fthrough F, wherein n may be 2, or an integer higher than 2, wherein the pore sizes of the filter Fthrough Frange from 200 microns to 10 Kilo Daltons, yielding filtrates and retentates, recycling either of said filtrates or said retentates or both, either separately or together, to any of steps b) or c) or both, at least one time, and isolating a decellularized small particle tissue from any of steps of the process. Both the product and process are novel.