Edward D O'Brien

US Patent:

59029757, May 11, 1999

Filed:

Dec 22, 1997

Appl. No.:

8/995306

Inventors:

Ethan J. Coulson - Quincy MA
Edward F. O'Brien - West Warwick RI
Charles M. Anastasia - Barrington RI
Alan M. Sadler - North Attleboro MA
Dale R. Sogge - Wrentham MA

Assignee:

Texas Instruments Incorporated - Dallas TX

International Classification:

H01H3/16

US Classification:

200 6191

Abstract:

An internal vehicular transmission range switch (10) has a movable contact support (20) which slides along a straight path in a recess formed between a housing having a base member (12) and cover (14) between first and second extremities in dependence upon the movement of the manual valve (4) to which it is coupled by an arm (18) extending from the support through a slot (16) formed in the housing. An elongated slider having a lower (20e) and upper (20d) blade portions received in respective channels (12a, 14a) formed in the housing integrally attached to the movable contact support blocks ingress of contaminant particles into the recess while permitting fluid flow into and out of the recess. A second embodiment (10') has a generally U-shaped member (18') having one leg (18a') attached to the movable contact support and extending through an O-ring (24) in an end wall of the housing and a manual valve coupling arm (18c') formed at the distal end of a second leg (18b'). A third embodiment has an endless track (26) in which an elongated, flexible band (28) having opposite ends attached to the movable contact support (20) on opposite sides of manual valve coupling arm (18) blocks entry of contaminant particles through slot (16") in the housing through which arm (18) extends.

US Patent:

50048767, Apr 2, 1991

Filed:

Dec 20, 1988

Appl. No.:

7/286726

Inventors:

Dale R. Sogge - Randolph MA
Edward F. O'Brien - Providence RI
David A. Czarn - Cumberland RI

Assignee:

Texas Instruments Incorporated - Dallas TX

International Classification:

H01H 3534

US Classification:

200 83P

Abstract:

A pressure responsive switch having upper and lower contact assemblies with a snap acting member and an electrically conductive member sandwiched therebetween. The assemblies each include an insulating body with a hollow center and an electrically conductive member having a contact in the center portion and extending externally of the body. The snap acting member is in constant engagement with the sandwiched conductive member and normally in engagement with the electrically conductive member of the upper assembly. When a pressure is applied which is sufficient to cause the snap acting member to snap into its second stable state, the connection thereof with the electrically conductive member in the upper contact assembly is broken and connection is made with the electrically conductive member in the lower assembly. The switch is normally closed by removing the portion of the electrically conductive member in the lower assembly which extends externally thereof. The switch can be provided normally open by removing the portion of the electrically conductive member in the upper assembly which extends externally thereof.

US Patent:

20230125810, Apr 27, 2023

Filed:

Nov 25, 2020

Appl. No.:

17/780831

Inventors:

- Cambridge MA, US
Edward J. O'BRIEN - Arlington MA, US
Sheri Lynn SIMMONS - Brookline MA, US
David COOK - Brookline MA, US
Matthew R. HENN - Cambridge MA, US
Christopher B. FORD - Swampscott MA, US
Divya BALASUBRAMANIAN - Arlington MA, US
Ambar PIÑA - Boston MA, US
Liyang DIAO - Belmont MA, US
Meghan CHAFEE - Acton MA, US
Marin VULIC - Boston MA, US
Madhumitha NANDAKUMAR - Belmont CA, US
Sumon DATTA - Cambridge MA, US
Lata JAYARAMAN - Cambridge MA, US

Assignee:

Seres Therapeutics, Inc. - Cambridge MA

International Classification:

A61K 35/741
A61P 35/00
A61P 37/00

Abstract:

Provided herein are bacterial compositions that are useful for treating and preventing complications and side effects associated with a disease or disorder, such as those associated with dysbiosis of a gastrointestinal tract. The bacterial compositions disclosed herein are designed to exhibit one or more functional features that are useful for the treatment of such diseases and disorders.

US Patent:

20210121505, Apr 29, 2021

Filed:

Mar 29, 2019

Appl. No.:

17/043545

Inventors:

- Cambridge MA, US
Edward J. O'BRIEN - Arlington MA, US
Sumon DATTA - Boston MA, US

Assignee:

Seres Therapeutics, Inc. - Cambridge MA

International Classification:

A61K 35/742
A61P 37/06
A61P 1/00
A61P 1/04

Abstract:

Provided herein are bacterial compositions that are useful for treating and preventing complications and side effects associated with an inflammatory bowel disease.

US Patent:

20210008128, Jan 14, 2021

Filed:

Aug 14, 2018

Appl. No.:

16/639492

Inventors:

- Cambridge MA, US
Alice Peiyu LIOU - Somerville MA, US
Elizabeth Moritz HALVORSEN - Malden MA, US
Gregory MCKENZIE - Arlington MA, US
Edward J. O'BRIEN - Arlington MA, US
David COOK - Brookline MA, US

Assignee:

Seres Therapeutics, Inc. - Cambridge MA

International Classification:

A61K 35/745
A61P 1/16
A61K 31/58

Abstract:

The invention provides compositions and methods for use in the treatment and prevention of cholestatic diseases.

US Patent:

20200353018, Nov 12, 2020

Filed:

Oct 30, 2018

Appl. No.:

16/760757

Inventors:

- Cambridge MA, US
Jessica BRYANT - Cambridge MA, US
Edward J. O'BRIEN - Arlington MA, US

Assignee:

Seres Therapeutics, Inc. - Cambridge MA

International Classification:

A61K 35/742
A61P 31/04

Abstract:

The present invention relates to compositions and methods for reducing the carriage of antibiotic resistance genes.