Edwin A Pomerantz

US Patent:

50811576, Jan 14, 1992

Filed:

Feb 6, 1991

Appl. No.:

7/652195

Inventors:

Edwin Pomerantz - Woodland Hills CA

Assignee:

Zila Pharmaceuticals, Inc. - Phoenix AZ

International Classification:

A61K 908
A61K 3160
A61K 3169
A61K 3172

US Classification:

514781

Abstract:

A film-forming composition for topical application of medicaments to body tissues. The film-forming composition includes hydroxypropyl cellulose; a non-toxic volatile solvent for said hydroxypropyl cellulose and said reaction product, and an esterification agent which reacts with the hydroxypropyl cellulose to form a reaction product which is soluble in the solvent. The medicinal compound is selected from the group consisting of hydrocortisone, hydrocortisone acetate, betamethasone dipropionate, triamainolone acetonide, lidocaine hydrochloride, dibucaine hydrochloride.

US Patent:

50811584, Jan 14, 1992

Filed:

Mar 8, 1990

Appl. No.:

7/474743

Inventors:

Edwin Pomerantz - Woodland Hills CA

Assignee:

Zila Pharmaceuticals, Inc. - Phoenix AZ

International Classification:

C08L 126
A61K 908
A61K 3160
A61K 3169
A61K 3172

US Classification:

514781

Abstract:

Medicated protective films are formed in situ on body tissue by applying a composition comprising (a) hydroxypropyl cellulose; (b) an esterification agent which reacts with the hydroxypropyl cellulose to form a reaction product which is soluble in the solvent of (c), but insoluble in body fluids at body temperatures; and (c) a nontoxic volatile solvent for said hydroxypropyl cellulose and said reaction products; and (d) a separate medicinal component. The films are tough, resilient and adhesive to body tissue including the mucosa.

US Patent:

58826270, Mar 16, 1999

Filed:

Sep 3, 1997

Appl. No.:

8/930437

Inventors:

Edwin Pomerantz - Woodland Hills CA

Assignee:

Zila Pharmaceuticals, Inc. - Phoenix AZ

International Classification:

A61K 4900

US Classification:

424 97

Abstract:

A method for in-vivo detection of premalignant oral lesions and oral carcinomas includes the step of applying to oral tissue a non-toxic dye other than toluidine blue O, selected from compounds having structure ##STR1## and ionic derivatives thereof, wherein R. sup. 1 is H, or lower alkyl group or N(R. sup. 3)2, R. sup. 2 is N, S or O, and R. sup. 3 is H or a lower alkyl group.