Ronald P. Taylor - Charlottesville VA William M. Sutherland - Earlysville VA Craig Reist - Charlottesville VA Eleanor L. Wright - Earlysville VA Donna Webb - Charlottesville VA Ronald Labuguen - Charlottesville VA
Assignee:
University of Virginia Patent Foundation - Charlottesville VA
International Classification:
A61K 39395 A61K 3940 A61K 3942
US Classification:
4241361
Abstract:
Mammalian red blood cells are used to safely and rapidly neutralize and/or clear antigens or immunogens from the circulatory system by binding to the RBC a monoclonal antibody specific for a receptor (CR1) on the RBC, which monoclonal antibody is chemically bound to a second Mab specific for the antigen to be cleared from the circulatory system. These chemically cross-linked monoclonal antibody heteropolymers may be injected directly into the patient's circulatory system. Alternatively, red blood cells, extracted from the patient or provided by a suitable donor, are bound to the Mab complex and returned to the system.
Mammalian Primate Erythrocyte Bound Heteropolymerized Monoclonal Antibodies And Methods Of Use Thereof
Ronald P. Taylor - Charlottesville VA William M. Sutherland - Earlysville VA Craig Reist - Charlottesville VA Eleanor L. Wright - Earlysville VA Donna Webb - Charlottesville VA Ronald Labuguen - Charlottesville VA
Assignee:
University of Virginia Patent Foundation - Charlottesville VA
International Classification:
A61K 3518 A61K 39395 A61K 3940 A61K 3942
US Classification:
424 9373
Abstract:
Mammalian red blood cells are used to safely and rapidly neutralize and/or clear antigens or immunogens from the circulatory system by binding to the RBC a monoclonal antibody specific for a receptor (CR1) on the RBC, which monoclonal antibody is chemically bound to a second Mab specific for the antigen to be cleared from the circulatory system. These chemically cross-linked monoclonal antibody heteropolymers may be injected directly into the patient's circulatory system. Alternatively, red blood cells, extracted from the patient or provided by a suitable donor, are bound to the Mab complex and returned to the system.
Cold Spring Elementary School Santa Barbara CA 1950-1951, Montecito Elementary School Santa Barbara CA 1952-1957, Santa Barbara Junior High School Santa Barbara CA 1957-1959
He married Eleanor Wright and worked as a telephone repairer for a year, until, with the help of the GI bill, he took a degree in electrical engineering at Cornell University, New York state (1950), supplementing his income by running the university's radio transmitter and the electronics for their