Elizabeth A Hauser

US Patent:

8097415, Jan 17, 2012

Filed:

Sep 23, 2010

Appl. No.:

12/888937

Inventors:

Jeffery M. Vance - Coral Gables FL, US
Pascal J. Goldschmidt - Miami FL, US
Simon G. Gregory - Durham NC, US
William E. Kraus - Hillsborough NC, US
Elizabeth R. Hauser - Durham NC, US

Assignee:

Duke University - Durham NC

International Classification:

C12Q 1/68
C07H 21/02
C07H 21/04
C12P 19/34

US Classification:

435 611, 435 61, 435 612, 435 912, 536 231, 536 235, 536 2431

Abstract:

The present invention provides methods of identifying a subject having an increased or decreased risk of developing cardiovascular disease, comprising:.

US Patent:

20090087844, Apr 2, 2009

Filed:

Feb 14, 2008

Appl. No.:

12/031528

Inventors:

Jeffery M. Vance - Coral Gables FL, US
Pascal J. Goldschmidt - Miami FL, US
Simon G. Gregory - Durham NC, US
William E. Kraus - Hillsborough NC, US
Elizabeth R. Hauser - Durham NC, US

International Classification:

C12Q 1/68

US Classification:

435 6

Abstract:

The present invention provides methods of identifying a subject having an increased or decreased risk of developing cardiovascular disease, comprising:

US Patent:

20130017962, Jan 17, 2013

Filed:

Sep 2, 2010

Appl. No.:

12/874635

Inventors:

Jeffery M. Vance - Coral Gables FL, US
Pascal J. Goldschmidt - Miami FL, US
Simon G. Gregory - Durham NC, US
William E. Kraus - Hillsborough NC, US
Elizabeth R. Hauser - Durham NC, US

International Classification:

C12Q 1/68
G01N 27/447
C40B 30/04

US Classification:

506 9, 435 611, 204450

Abstract:

The present invention provides methods of identifying a subject having an increased or decreased risk of developing cardiovascular disease, comprising: a) correlating the presence of one or more genetic markers in chromosome 3q13.31 with an increased or decreased risk of developing cardiovascular disease; and b) detecting the one or more genetic markers of step (a) in the subject, thereby identifying the subject as having an increased or decreased risk of developing cardiovascular disease. Also provided are methods of identifying subjects with cardiovascular disease as having a good or poor prognosis, as well as methods of identifying effective treatment regimens for cardiovascular disease, based on correlation with genetic markers in chromosome 3q13.31.

US Patent:

20130324416, Dec 5, 2013

Filed:

Jan 16, 2012

Appl. No.:

13/351042

Inventors:

Jeffery M. Vance - Coral Gables FL, US
Pascal J. Goldschmidt - Miami FL, US
Simon G. Gregory - Durham NC, US
William E. Kraus - Hillsborough NC, US
Elizabeth R. Hauser - Durham NC, US

International Classification:

C12Q 1/68

US Classification:

506 2, 435 611

Abstract:

The present invention provides methods of identifying a subject having an increased or decreased risk of developing cardiovascular disease, comprising: a) correlating the presence of one or more genetic markers in chromosome 3q13.31 with an increased or decreased risk of developing cardiovascular disease; and b) detecting the one or more genetic markers of step (a) in the subject, thereby identifying the subject as having an increased or decreased risk of developing cardiovascular disease. Also provided are methods of identifying subjects with cardiovascular disease as having a good or poor prognosis, as well as methods of identifying effective treatment regimens for cardiovascular disease, based on correlation with genetic markers in chromosome 3q13.31.