Eric Hu

US Patent:

20120195982, Aug 2, 2012

Filed:

Jan 28, 2011

Appl. No.:

13/016213

Inventors:

Eric G. Hu - Basking Ridge NJ, US
Kun Hu - Beijing, CN
Chenguang Liu - Beijing, CN
Zonggang Chen - Beijing, CN
Fuzai Cui - Beijing, CN

Assignee:

Beijing Allgens Medical Science & Technology Co., Ltd. - Beijing

International Classification:

A61K 33/06
A61P 19/00

US Classification:

424696

Abstract:

An injectible, biocompatible synthetic bone growth composition comprising a mineralized collagen and a calcium sulfate component. The composition is formed into injectible formulation that may be provided at the site of a skeletal defect via minimally invasive manner. An osteoinductive component may be further added, either before or after forming the unitary article. The composition may be formulated as a paste or putty and facilitates bone growth and/or repair.

US Patent:

20120308530, Dec 6, 2012

Filed:

Jun 3, 2011

Appl. No.:

13/152649

Inventors:

Eric G Hu - Basking Ridge NJ, US
Kun Hu - Beijing, CN
Yongjuan Ren - Beijing, CN

International Classification:

A61K 35/30
A61P 25/16
A61P 25/08
C12N 5/071
C12N 5/0797

US Classification:

424 937, 435366, 435368

Abstract:

This invention disclosure provides culture surface compositions and methods that control the NPCs and NSCs, and/or MSCs to either largely maintain their phenotypes, or differentiate on these culture surfaces in guided lineage. The culture surface composition can be constructed to contain either OH functional groups, or —NHgroups to control the adherence, migration, proliferation and differentiation of MSCs, providing a methods to direct NSCs lineage specification in neural tissue engineering for a wide variety of neurological diseases.

US Patent:

20140194363, Jul 10, 2014

Filed:

Jan 8, 2013

Appl. No.:

13/736371

Inventors:

Eric Gang Hu - Basking Ridge NJ, US

Assignee:

Beijing Allgens Medical and Technology Co, Ltd - Beijing

International Classification:

A61K 38/39

US Classification:

514 167

Abstract:

The present invention provides a compression-resistant collagen-based artificial bone repair material that could be used for bone defect repair at human load-bearing sites. Such material has a composition and structure of self-assembled nano-sized calcium phosphate salt and collagen molecules, thereby possessing a biomimetic mineralization structure similar to the natural bone. On the aspect of mechanical properties, such material has a similar mechanical strength to human cortical bone, which makes it suitable for repairing bone defects at human load-bearing sites. The present invention further provides preparation methods of such Compression-resistant collagen-based artificial bone repair material.