Eric L Negre
age ~61
from Gaithersburg, MD
Eric Negre Phones & Addresses
- Gaithersburg, MD
- 4890 Battery Ln, Bethesda, MD 20814
Us Patents
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Peptide Inhibitors Of Fibronectin And Related Collagen-Binding Proteins
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US Patent:54911303, Feb 13, 1996
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Filed:Nov 10, 1992
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Appl. No.:7/973235
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Inventors:David D. Roberts - Bethesda MD
Henry C. Krutzsch - Bethesda MD
John M. Sipes - Cabin John MD
Eric Negre - Bethesda MD -
Assignee:The United States of America as represented by the Department of Health
and Human Services - Washington DC -
International Classification:A61K 3800
C07K 700
C07K 706
C07K 708 -
US Classification:514 13
-
Abstract:Peptides derived from the second type 1 repeat of human endothelial cell thrombospondin which bind to the gelatin-binding domain of fibronectin have been isolated and synthetically produced. The peptides can be used to bind to fibronectin or other related collagen-binding proteins to inhibit fibronectin-dependent cell adhesion to collagen matrices and to inhibit interactions with collagen of other proteins that share homologies with the gelatin-binding domain of fibronectin.
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Peptide Inhibitors Of Fibronectin And Related Collagen-Binding Proteins
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US Patent:58497013, Dec 15, 1998
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Filed:Jun 5, 1995
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Appl. No.:8/462720
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Inventors:David D. Roberts - Bethesda MD
Henry C. Krutzsch - Bethesda MD
John M. Sipes - Cabin John MD
Eric Negre - Bethesda MD -
Assignee:The United States of America as represented by the Department of Health
and Human Services - Washington DC -
International Classification:A61K 3800
C07K 706
C07K 708
C07K 700 -
US Classification:514 12
-
Abstract:Peptides derived from the second type 1 repeat of human endothelial cell thrombospondin which bind to the gelatin-binding domain of fibronectin have been isolated and synthetically produced. The peptides can be used to bind to fibronectin or other related collagen-binding proteins to inhibit fibronectin-dependent cell adhesion to collagen matrices and to inhibit interactions with collagen of other proteins that share homologies with the gelatin-binding domain of fibronectin.
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